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- W4387432488 abstract "This study introduces a novel hydroxymethylation method using DMSO. A wide range of 1,3-dicarbonyls underwent hydroxymethylation efficiently to afford the corresponding hydroxylated products in yields ranging from 73 % to 98 % under basic conditions, with formaldehyde generated from DMSO decomposition catalyzed by oxalyl chloride and hydrochloric acid in 1,4-dioxane. This method offers a more efficient alternative to existing approaches, expanding synthetic possibilities." @default.
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- W4387432488 date "2023-11-01" @default.
- W4387432488 modified "2023-10-18" @default.
- W4387432488 title "Straightforward hydroxymethylation of 1,3-dicarbonyls with dimethyl sulfoxide" @default.
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- W4387432488 doi "https://doi.org/10.1016/j.tet.2023.133689" @default.
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