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- W4387432874 abstract "Stevens-Johnson syndrome (SJS), also known as the multifactorial erythematous drug eruption, is a class of adverse reactions of the skin and mucous membranes primarily caused by drug allergy often involving the oral cavity, eyes, and external genital mucosa, generally accompanied by fever, and can be life-threatening in severe cases. In February 2022, the Department of Stomatology, the First Affiliated Hospital of Zhengzhou University admitted a patient with huge inflammatory hyperplasia of bilateral lingual margins secondary to SJS. Upon admission, no other obvious symptoms were observed except for tongue hyperplasia. The patient suffered from a severe adverse drug reaction caused by acetaminophen 2 months ago and was complicated by liver dysfunction and pulmonary infection. After 1 month of treatment and rehabilitation, he developed a secondary tongue mass and was subsequently admitted to Dept. of Oral and Maxillofacial Surgery Ward 2, the First Affiliated Hospital of Zhengzhou University. After completing the examination, the tongue mass was surgically removed. After a follow-up of 11 months, the patient's condition was satisfactory and no temporary discomfort was observed. The case of tongue mass secondary to SJS is extremely rare. If a stomatologist encounters a similar case, we should carefully inquire about the drug allergy history and recent medication history, and be alert to whether or not they had adverse drug reactions recently.史蒂文斯-约翰逊综合征（SJS）又称重症多形红斑型药疹，为一类主要由药物过敏所引起的皮肤和黏膜的不良反应，常累及口腔、眼及外生殖器黏膜，常伴发热，严重者可危及生命。郑州大学第一附属医院口腔科于2022年2月收治1名SJS继发双侧舌缘巨大炎性增生物的患者，入院时除舌增生物无其他明显症状。患者曾于2月前因服用对乙酰氨基酚产生严重药物不良反应致SJS，合并肝功异常及肺部感染，治疗康复1月后继发舌部增生物，遂收入郑州大学第一附属医院口腔颌面外二科，完善检查后手术切除舌部增生物，随访11个月，患者情况可，无不适。SJS继发舌增生物的病例极其罕见，口腔科医师如遇类似病例，应详细询问药物过敏史及近期用药史，警惕其是否近期发生过药物不良反应。." @default.
- W4387432874 created "2023-10-09" @default.
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- W4387432874 date "2023-10-01" @default.
- W4387432874 modified "2023-10-09" @default.
- W4387432874 title "Stevens-Johnson syndrome secondary to massive inflammatory hyperplasia of bilateral lingual margins: a case report and literature review." @default.
- W4387432874 doi "https://doi.org/10.7518/hxkq.2023.2023086" @default.
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