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- W4387435333 abstract "The aim of this study was to provide evidence of the domestic benefits of introducing an integrative genomic analysis from the one health approach in the national surveillance of Salmonella enterica between 1997-2017 in Colombia. Data of Salmonella from clinical laboratory-based surveillance between 1997-2017 and from national cross-sectional study at chicken retail stores in Colombia were compared using a phenotypic, molecular and genomic approaches. Additional analysis by serovar using single nucleotide polymorphism were developed to increase the resolution of the relatedness between the interfaces. Locally, the diversity and pathogenic factors of the prevalent Salmonella enterica serovars associated to foodborne disease in Colombia were described using laboratory, pulse field gel electrophoresis and whole genome sequencing data. For example, the resolution of pulse field gel electrophoresis allowed the description of two main foodborne clusters of S. Enteritidis isolates, which were expanded to eight foodborne clades using whole genome sequencing. Likewise, virulence factors and antimicrobial resistance determinants, and mobile genetic elements that converged in the foodborne clades should be considered a public health concern in Colombia. All results by serovar were compiled in an interactive easy to share reports. WGS is a technology that provides a precise assessment of emerging foodborne risks as the Salmonella foodborne clades, but it requires an integrative and continued collaboration between the stakeholders across the One Health sectors to promote appropriated actions and policies in public health." @default.
- W4387435333 created "2023-10-09" @default.
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- W4387435333 date "2023-10-01" @default.
- W4387435333 modified "2023-10-11" @default.
- W4387435333 title "A one health approach based on genomics for enhancing the Salmonella enterica surveillance in Colombia" @default.
- W4387435333 doi "https://doi.org/10.1016/j.ijregi.2023.09.008" @default.
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