FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387439587> ?p ?o ?g. }

• W4387439587 endingPage "9" @default.
• W4387439587 startingPage "1" @default.
• W4387439587 abstract "AbstractBackground Volumetric Modulated Arc Therapy (VMAT) offers better conformity, homogeneity and sparing of the heart and ipsilateral lung for locoregional radiotherapy in left-sided breast cancer compared to three-dimensional conformal radiotherapy (3D-CRT). However, conventional coplanar VMAT (cVMAT) can result in higher doses to the normal tissue on the contralateral side. This study investigates a non-coplanar VMAT-technique (ncVMAT) to mitigate this issue.Material and methods CT series of 20 left sided breast cancer patients were included for planning of locoregional breast radiotherapy including internal mammary nodes (IMN). Three treatment plans; 3D-CRT, cVMAT and ncVMAT, were generated for each patient with a prescription dose of 40.05 Gy in 15 fractions. Both VMAT-techniques consisted of a single arc in the axial plane, while ncVMAT included an additional arc in the sagittal plane. All plans were optimized to cover the clinical target volume (CTV) by 38.05 Gy for the breast and 36.05 Gy for lymph nodes, with as low as possible dose to organs at risk.Results Full CTV coverage was achieved for all plans. Both cVMAT and ncVMAT delivered more conformal and homogeneous target doses than 3D-CRT. Doses to the heart and ipsilateral lung were significantly lower with ncVMAT compared to both cVMAT and 3D-CRT. ncVMAT reduced doses to both the contralateral breast and lung compared to cVMAT and achieved levels similar to 3D-CRT for the contralateral breast and moderately higher doses for the contralateral lung. Delivery of high doses (>30 Gy) to the contralateral side was completely avoided with ncVMAT, contrary to the results for cVMAT and 3D-CRT.Conclusion ncVMAT reduced doses to the heart and ipsilateral lung as compared to both cVMAT and 3D-CRT. All contralateral dose metrics were reduced with the novel ncVMAT technique compared to cVMAT, and the mean contralateral breast doses were similar to 3D-CRT.Keywords: RadiotherapyVMATlocoregional breastautomationIMN Data availability statementThe data that support the findings of this study are available from the corresponding author, [JF], upon request.Disclosure statementNo potential conflict of interest was reported by the authors.Additional informationFundingThe project was partly funded by the Research and innovation funds from St. Olavs hospital." @default.
• W4387439587 created "2023-10-10" @default.
• W4387439587 creator A5000850932 @default.
• W4387439587 creator A5019198132 @default.
• W4387439587 creator A5024618758 @default.
• W4387439587 creator A5028195819 @default.
• W4387439587 creator A5030985522 @default.
• W4387439587 creator A5055734884 @default.
• W4387439587 creator A5069840693 @default.
• W4387439587 date "2023-10-09" @default.
• W4387439587 modified "2023-10-10" @default.
• W4387439587 title "Locoregional breast radiotherapy including IMN: optimizing the dose distribution using an automated non-coplanar VMAT-technique" @default.
• W4387439587 cites W1978537515 @default.
• W4387439587 cites W2024160646 @default.
• W4387439587 cites W2032559105 @default.
• W4387439587 cites W2034163082 @default.
• W4387439587 cites W2036934183 @default.
• W4387439587 cites W2037171241 @default.
• W4387439587 cites W2043866992 @default.
• W4387439587 cites W2056251349 @default.
• W4387439587 cites W2070710666 @default.
• W4387439587 cites W2073295964 @default.
• W4387439587 cites W2073662365 @default.
• W4387439587 cites W2081908301 @default.
• W4387439587 cites W2092408666 @default.
• W4387439587 cites W2100025800 @default.
• W4387439587 cites W2129825983 @default.
• W4387439587 cites W2143561393 @default.
• W4387439587 cites W2154375587 @default.
• W4387439587 cites W2176010689 @default.
• W4387439587 cites W2332829713 @default.
• W4387439587 cites W2468317446 @default.
• W4387439587 cites W2520230173 @default.
• W4387439587 cites W2531894878 @default.
• W4387439587 cites W2598117381 @default.
• W4387439587 cites W2788151071 @default.
• W4387439587 cites W2897643122 @default.
• W4387439587 cites W2931171730 @default.
• W4387439587 cites W2943776193 @default.
• W4387439587 cites W2953769967 @default.
• W4387439587 cites W3039259782 @default.
• W4387439587 cites W3080060554 @default.
• W4387439587 cites W3080255616 @default.
• W4387439587 cites W3088516349 @default.
• W4387439587 cites W3091299005 @default.
• W4387439587 cites W3119349984 @default.
• W4387439587 cites W3215549417 @default.
• W4387439587 cites W4223653864 @default.
• W4387439587 cites W4226295831 @default.
• W4387439587 cites W4247010434 @default.
• W4387439587 cites W4316363190 @default.
• W4387439587 doi "https://doi.org/10.1080/0284186x.2023.2264488" @default.
• W4387439587 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37812070" @default.
• W4387439587 hasPublicationYear "2023" @default.
• W4387439587 type Work @default.
• W4387439587 citedByCount "0" @default.
• W4387439587 crossrefType "journal-article" @default.
• W4387439587 hasAuthorship W4387439587A5000850932 @default.
• W4387439587 hasAuthorship W4387439587A5019198132 @default.
• W4387439587 hasAuthorship W4387439587A5024618758 @default.
• W4387439587 hasAuthorship W4387439587A5028195819 @default.
• W4387439587 hasAuthorship W4387439587A5030985522 @default.
• W4387439587 hasAuthorship W4387439587A5055734884 @default.
• W4387439587 hasAuthorship W4387439587A5069840693 @default.
• W4387439587 hasConcept C121608353 @default.
• W4387439587 hasConcept C126322002 @default.
• W4387439587 hasConcept C126838900 @default.
• W4387439587 hasConcept C142724271 @default.
• W4387439587 hasConcept C178910020 @default.
• W4387439587 hasConcept C201645570 @default.
• W4387439587 hasConcept C2777714996 @default.
• W4387439587 hasConcept C2779720271 @default.
• W4387439587 hasConcept C2908623805 @default.
• W4387439587 hasConcept C2989005 @default.
• W4387439587 hasConcept C509974204 @default.
• W4387439587 hasConcept C530470458 @default.
• W4387439587 hasConcept C71924100 @default.
• W4387439587 hasConceptScore W4387439587C121608353 @default.
• W4387439587 hasConceptScore W4387439587C126322002 @default.
• W4387439587 hasConceptScore W4387439587C126838900 @default.
• W4387439587 hasConceptScore W4387439587C142724271 @default.
• W4387439587 hasConceptScore W4387439587C178910020 @default.
• W4387439587 hasConceptScore W4387439587C201645570 @default.
• W4387439587 hasConceptScore W4387439587C2777714996 @default.
• W4387439587 hasConceptScore W4387439587C2779720271 @default.
• W4387439587 hasConceptScore W4387439587C2908623805 @default.
• W4387439587 hasConceptScore W4387439587C2989005 @default.
• W4387439587 hasConceptScore W4387439587C509974204 @default.
• W4387439587 hasConceptScore W4387439587C530470458 @default.
• W4387439587 hasConceptScore W4387439587C71924100 @default.
• W4387439587 hasLocation W43874395871 @default.
• W4387439587 hasLocation W43874395872 @default.
• W4387439587 hasOpenAccess W4387439587 @default.
• W4387439587 hasPrimaryLocation W43874395871 @default.
• W4387439587 hasRelatedWork W1972868954 @default.
• W4387439587 hasRelatedWork W2003305474 @default.
• W4387439587 hasRelatedWork W2041795146 @default.
• W4387439587 hasRelatedWork W2070718209 @default.

• next