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- W4387447737 abstract "Abstract This pioneering study explores the structural intricacies of therapeutic β-glucan in Shiitake ( Lentinula edodes ), i.e. Lentinan (LNT). Lentinan, a neutral polysaccharide [β-(1,3; 1,6) glucan], exists in three forms; single, double, and triple-helical, but conformation-dependent bioactivity studies are lacking. Many more, methods to estimate and quantify conformation-dependent forms can translate to structure-functionality relationships. In this context, we meticulously assessed indigenous Shiitake accessions from Northeast India, unveiling the conformational spectrum of LNT through an innovative pipeline. The experiment approached the simultaneous estimation of total glucan (TG), triple helical glucan (THG), and single-double helical glucan (SDG). Profiling revealed the exceptional LNT content in DMRO-623 (TG: 46.74%, SDG: 9.34%, THG: 37.39%) which emerged as the highest documented to date. Beyond the culinary delight, this research and the novel approach to LNT quantification will create a pivotal platform for advanced mushroom research, offering prospects for novel discoveries, innovative applications, and therapeutic potential." @default.
- W4387447737 created "2023-10-10" @default.
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- W4387447737 date "2023-10-09" @default.
- W4387447737 modified "2023-10-11" @default.
- W4387447737 title "A novel method for detecting conformation-dependent β-glucans - Single, double, and triple-helical from Shiitake mushroom" @default.
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- W4387447737 doi "https://doi.org/10.21203/rs.3.rs-3420056/v1" @default.
- W4387447737 hasPublicationYear "2023" @default.
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