Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387453341> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W4387453341 abstract "Recently, we have achieved a significant milestone with the creation of the Fly Cell Atlas. This single-nuclei atlas encompasses the entire fly, covering the entire head and body, in addition to all major organs. This atlas catalogs hundreds to thousands of cell types, of which we annotated 250. This still leaves many clusters to be fully characterized, in particular in the brain. Furthermore, with single-nuclei sequencing, all information about the spatial location of the cells and of the mRNAs within these cells is lost. Here, we provide a solution to this problem. In a proof of concept study, we have applied spatial transcriptomics using a selected gene panel to pinpoint the locations of 150 mRNA species in the adult fly. This enabled us to map unknown cell types identified in the Fly Cell Atlas to their spatial locations in the brain. Additionally, spatial transcriptomics discovered interesting principles of mRNA localization in large crowded muscle cells that may spark future mechanistic investigations. Furthermore, we present a set of computational tools that will allow for easier integration of spatial transcriptomics and single-cell datasets." @default.
- W4387453341 created "2023-10-10" @default.
- W4387453341 creator A5001053440 @default.
- W4387453341 creator A5002137087 @default.
- W4387453341 creator A5017523286 @default.
- W4387453341 creator A5018784559 @default.
- W4387453341 creator A5022036519 @default.
- W4387453341 creator A5034973395 @default.
- W4387453341 creator A5051456216 @default.
- W4387453341 creator A5079968111 @default.
- W4387453341 creator A5087265062 @default.
- W4387453341 date "2023-10-06" @default.
- W4387453341 modified "2023-10-11" @default.
- W4387453341 title "Spatial transcriptomics in adult<i>Drosophila</i>reveals new cell types in the brain and identifies subcellular mRNA patterns in muscles" @default.
- W4387453341 doi "https://doi.org/10.1101/2023.10.06.561233" @default.
- W4387453341 hasPublicationYear "2023" @default.
- W4387453341 type Work @default.
- W4387453341 citedByCount "0" @default.
- W4387453341 crossrefType "posted-content" @default.
- W4387453341 hasAuthorship W4387453341A5001053440 @default.
- W4387453341 hasAuthorship W4387453341A5002137087 @default.
- W4387453341 hasAuthorship W4387453341A5017523286 @default.
- W4387453341 hasAuthorship W4387453341A5018784559 @default.
- W4387453341 hasAuthorship W4387453341A5022036519 @default.
- W4387453341 hasAuthorship W4387453341A5034973395 @default.
- W4387453341 hasAuthorship W4387453341A5051456216 @default.
- W4387453341 hasAuthorship W4387453341A5079968111 @default.
- W4387453341 hasAuthorship W4387453341A5087265062 @default.
- W4387453341 hasBestOaLocation W43874533411 @default.
- W4387453341 hasConcept C104317684 @default.
- W4387453341 hasConcept C105702510 @default.
- W4387453341 hasConcept C111919701 @default.
- W4387453341 hasConcept C1491633281 @default.
- W4387453341 hasConcept C150194340 @default.
- W4387453341 hasConcept C162317418 @default.
- W4387453341 hasConcept C169760540 @default.
- W4387453341 hasConcept C189014844 @default.
- W4387453341 hasConcept C2776673561 @default.
- W4387453341 hasConcept C2780972224 @default.
- W4387453341 hasConcept C2781020372 @default.
- W4387453341 hasConcept C41008148 @default.
- W4387453341 hasConcept C54355233 @default.
- W4387453341 hasConcept C70721500 @default.
- W4387453341 hasConcept C86803240 @default.
- W4387453341 hasConceptScore W4387453341C104317684 @default.
- W4387453341 hasConceptScore W4387453341C105702510 @default.
- W4387453341 hasConceptScore W4387453341C111919701 @default.
- W4387453341 hasConceptScore W4387453341C1491633281 @default.
- W4387453341 hasConceptScore W4387453341C150194340 @default.
- W4387453341 hasConceptScore W4387453341C162317418 @default.
- W4387453341 hasConceptScore W4387453341C169760540 @default.
- W4387453341 hasConceptScore W4387453341C189014844 @default.
- W4387453341 hasConceptScore W4387453341C2776673561 @default.
- W4387453341 hasConceptScore W4387453341C2780972224 @default.
- W4387453341 hasConceptScore W4387453341C2781020372 @default.
- W4387453341 hasConceptScore W4387453341C41008148 @default.
- W4387453341 hasConceptScore W4387453341C54355233 @default.
- W4387453341 hasConceptScore W4387453341C70721500 @default.
- W4387453341 hasConceptScore W4387453341C86803240 @default.
- W4387453341 hasLocation W43874533411 @default.
- W4387453341 hasOpenAccess W4387453341 @default.
- W4387453341 hasPrimaryLocation W43874533411 @default.
- W4387453341 hasRelatedWork W1523541591 @default.
- W4387453341 hasRelatedWork W1524478684 @default.
- W4387453341 hasRelatedWork W1967068856 @default.
- W4387453341 hasRelatedWork W2012519212 @default.
- W4387453341 hasRelatedWork W2592984741 @default.
- W4387453341 hasRelatedWork W3008241868 @default.
- W4387453341 hasRelatedWork W3040016123 @default.
- W4387453341 hasRelatedWork W3214912135 @default.
- W4387453341 hasRelatedWork W4249039539 @default.
- W4387453341 hasRelatedWork W4317802300 @default.
- W4387453341 isParatext "false" @default.
- W4387453341 isRetracted "false" @default.
- W4387453341 workType "article" @default.