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- W4387455000 abstract "Emerging evidence highlights the interconnection of the gut-skin microbiota in disease pathogenesis, progression, and as a potential therapeutic target for the management of inflammatory-driven cutaneous diseases. Although not fully understood, recent research has indicated that commensal microbiota and the interaction of the gut-skin axis play an important role in maintaining the skin homeostasis. Dysbiosis and disruption of skin-gut microbiome may lead to impaired skin barrier function thus triggering downstream inflammatory responses involved in the development of inflammatory skin disorders, especially in atopic dermatitis, psoriasis, and hidradenitis suppurativa. Moreover, skin microbiome might also serve as adjunctive therapeutic modalities for treatment. Herein, we review the latest reports on the interrelationship between microbial dysbiosis and inflammatory cutaneous diseases as well as emerging microbiome-directed therapeutics in atopic dermatitis, psoriasis, and hidradenitis suppurativa." @default.
- W4387455000 created "2023-10-10" @default.
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- W4387455000 date "2023-10-01" @default.
- W4387455000 modified "2023-10-12" @default.
- W4387455000 title "Targeting Dysbiosis in Psoriasis, Atopic Dermatitis, and Hidradenitis Suppurativa: An Updated Review of the Gut-Skin Axis and Microbiome-Directed Therapy" @default.
- W4387455000 doi "https://doi.org/10.1016/j.clindermatol.2023.09.019" @default.
- W4387455000 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37816413" @default.
- W4387455000 hasPublicationYear "2023" @default.
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