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• W4387473388 abstract "Institutes of dermatopathology are faced with considerable challenges including a continuously rising numbers of submitted specimens and a shortage of specialized health care practitioners. Basal cell carcinoma (BCC) is one of the most common tumors in the fair-skinned western population and represents a major part of samples submitted for histological evaluation. Digitalizing glass slides has enabled the application of artificial intelligence (AI)-based procedures. To date, these methods have found only limited application in routine diagnostics. The aim of this study was to establish an AI-based model for automated BCC detection.In three dermatopathological centers, daily routine practice BCC cases were digitalized. The diagnosis was made both conventionally by analog microscope and digitally through an AI-supported algorithm based on a U-Net architecture neural network.In routine practice, the model achieved a sensitivity of 98.23% (center 1) and a specificity of 98.51%. The model generalized successfully without additional training to samples from the other centers, achieving similarly high accuracies in BCC detection (sensitivities of 97.67% and 98.57% and specificities of 96.77% and 98.73% in centers 2 and 3, respectively). In addition, automated AI-based basal cell carcinoma subtyping and tumor thickness measurement were established.AI-based methods can detect BCC with high accuracy in a routine clinical setting and significantly support dermatopathological work." @default.
• W4387473388 created "2023-10-11" @default.
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• W4387473388 date "2023-10-09" @default.
• W4387473388 modified "2023-10-12" @default.
• W4387473388 title "Applying an artificial intelligence deep learning approach to routine dermatopathological diagnosis of basal cell carcinoma" @default.
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• W4387473388 doi "https://doi.org/10.1111/ddg.15180" @default.
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• W4387473388 hasPublicationYear "2023" @default.
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