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• W4387477401 abstract "Introduction Frailty has been proposed to be a marker for biological age and may increase the morbidity and mortality after cardiac surgery. Bioelectrical impedance analysis (BIA) is a non-invasive method used to assess body composition including muscle mass, fat and body cell mass which in turn projects the nutritional and hydration status of the patient. Phase angle (PA) is a parameter obtained from bioimpedance analysis and reflects nutritional status and thereby frailty of the patient and helps in preoperative risk assessment. We aim to find out whether bio electrical impedance derived low phase angle predict adverse outcomes in elderly cardiac surgical patients Methods An observational prospective study. After obtaining ethical clearance and approval from institutional review board, adult patients more than 60 years of age undergoing cardiac surgery using cardiopulmonary bypass were included . During the preoperative anaesthesia visit, trained research assistants recorded the phase angle with the use of In Body S 10 bioimpedance machine. Based on phase angle values, patients were grouped into two based on cut off value of median phase angle, (phase angle > 5.20),(phase angle < 5.20). Hours of ventilation, Duration of inotropic support, Length of ICU stay, Postoperative drainage for first 24 hours were analysed. Results 148 patients were enrolled. The mean age was 66.06±4.55 years (53-78). Subjects with PA cut off of <5.2 had significantly higher mean duration of inotropes (28.30±14.49 hrs) than with > 5.2 (20.40±20.81 hours, p=0.024). Chest tube drainage was significantly high among subjects with PA cut off of <5.2 (209.81±129.19 ml) than with >5.2 (132.36±113.16 ml) (p=0.001). There was no significant difference in the length of ICU stay and duration of mechanical ventilation between both groups. Discussion Biological age is more important than the chronological age in determining the increased risk in elderly patients undergoing cardiac surgery. Observational studies reported that low phase angle values were significant predictors of poor nutritional status, decreased muscular strength, frailty, morbidity and mortality. In our study patients with low phase angle required longer duration of inotropic supports. Malnutrition and perioperative anaemia may aggravate postoperative bleeding. We found that first 24 hour post operative drainage was higher in patients with low phase angle. Preoperative low phase angle may predict the adverse outcome in elderly patients undergoing cardiac surgery. Assessing frailty through phase angle values pre operatively might help in implementing necessary interventions" @default.
• W4387477401 created "2023-10-11" @default.
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• W4387477401 date "2023-10-01" @default.
• W4387477401 modified "2023-10-14" @default.
• W4387477401 title "Does Bioelectrical impedance derived phase angle predict adverse outcomes in elderly patients undergoing cardiac surgery?" @default.
• W4387477401 doi "https://doi.org/10.1053/j.jvca.2023.08.107" @default.
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