FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387477568> ?p ?o ?g. }

• W4387477568 endingPage "64" @default.
• W4387477568 startingPage "63" @default.
• W4387477568 abstract "Introduction Hypoxic brain injury is inevitable in half of the out of hospital cardiac arrest patients. This has created an increased burden on the cardiac critical care unit to deliver high quality services with limited resources. The ESC/ESICM 2021 guidelines are implemented to neuro-prognosticate comatose patients as an appropriate timely decision-making endeavor. This quality improvement project aims to assess the predictability of a quadruped integrative tools for neuro-prognostication. Methods An electronic record for 176 of total 193 out of hospital cardiac arrest patients was evaluated retrospectively. 16 patients were excluded due to missing or incomplete data and death on arrival. A neuro-prognostication score was calculated based on clinical examination, neurophysiology (Electroencephalogram and Somatosensory Evoked Potentials), Neuron-specific enolase biomarker and CT/MRI Head imaging. A Minitab statistical software was used for data analysis. The outcome was interpreted as Deaths due to primary hypoxic brain injury or withdrawal of life support treatment. Chi-square testing was used to evaluate the correlation between different diagnostic tests and outcome. Results Data collection has been ongoing since June 2021. Amongst 176 patients, 41.5% deaths with male predominance were observed. We confirmed the best predictors mentioned in guidelines had significant statistical influence for predicting poor outcome compatible with hypoxic neurological impairment. They are namely higher age, Miracle score >6, Initial rhythm as asystole or PEA, NPI less than 3, absent corneal or tracheal reflexes, myoclonus, abnormal EEG with burst suppression, highly malignant waves, status epilepticus, bilaterally absent SSEP N20 waves, loss of grey-white matter on CT head. Although gender and MRI had statistical insignificant correlation. This QI project also highlighted higher specificity (70-90%) in all eight prognostic tests but lower sensitivity (50-60%). The positive predictive value was highest for NPI, absence of corneal reflexes and abnormal CT head (85-100%). Only 13% of hypoxic brain injury patients had MRI as a second radiological test to conclude findings from the CT head in selected cases. 80% patients discharged from ICU had positive neurological outcomes with Cerebral performance category scale CPC 1-2. 92% of them were discharged home with an average LOS in hospital of 14 days. 10% of CPC 5 died for multifactorial reasons, 10% had CPC of 3 or 4 with average LOS of 52 days and 7% required repatriation to neurorehabilitation. Discussion Being able to make the right decision for all patient at the right time enhances best practice, allows for appropriate clinical decision and avoids prolonged ITU stay. So a robust, structured and multimodal neuroprognostication approach is necessary alongwith multidisciplinary meeting including intensivist, cardiologist, neurologist and radiologist. In each case, after 72 hours a neuroprognostication score was calculated based on the guidelines. Overall, all patients with more >2 markers of poor prognosis went for withdrawal of life sustaining therapy in their best interest." @default.
• W4387477568 created "2023-10-11" @default.
• W4387477568 creator A5010990375 @default.
• W4387477568 creator A5018737023 @default.
• W4387477568 creator A5025699743 @default.
• W4387477568 creator A5048530799 @default.
• W4387477568 creator A5059874316 @default.
• W4387477568 creator A5078219438 @default.
• W4387477568 creator A5084105423 @default.
• W4387477568 creator A5085447058 @default.
• W4387477568 creator A5087741417 @default.
• W4387477568 creator A5093033122 @default.
• W4387477568 creator A5093033123 @default.
• W4387477568 date "2023-10-01" @default.
• W4387477568 modified "2023-10-16" @default.
• W4387477568 title "ASSESSING UTILITY OF THE CURRENT NEUROPROGNOSTICATION MODALITIES FOR PREDICTING HYPOXIC BRAIN INJURY IN OUT OF HOSPITAL CARDIAC ARREST PATIENTS" @default.
• W4387477568 doi "https://doi.org/10.1053/j.jvca.2023.08.112" @default.
• W4387477568 hasPublicationYear "2023" @default.
• W4387477568 type Work @default.
• W4387477568 citedByCount "0" @default.
• W4387477568 crossrefType "journal-article" @default.
• W4387477568 hasAuthorship W4387477568A5010990375 @default.
• W4387477568 hasAuthorship W4387477568A5018737023 @default.
• W4387477568 hasAuthorship W4387477568A5025699743 @default.
• W4387477568 hasAuthorship W4387477568A5048530799 @default.
• W4387477568 hasAuthorship W4387477568A5059874316 @default.
• W4387477568 hasAuthorship W4387477568A5078219438 @default.
• W4387477568 hasAuthorship W4387477568A5084105423 @default.
• W4387477568 hasAuthorship W4387477568A5085447058 @default.
• W4387477568 hasAuthorship W4387477568A5087741417 @default.
• W4387477568 hasAuthorship W4387477568A5093033122 @default.
• W4387477568 hasAuthorship W4387477568A5093033123 @default.
• W4387477568 hasConcept C118552586 @default.
• W4387477568 hasConcept C126322002 @default.
• W4387477568 hasConcept C129692064 @default.
• W4387477568 hasConcept C161941745 @default.
• W4387477568 hasConcept C164705383 @default.
• W4387477568 hasConcept C177713679 @default.
• W4387477568 hasConcept C194828623 @default.
• W4387477568 hasConcept C2776296500 @default.
• W4387477568 hasConcept C2776376669 @default.
• W4387477568 hasConcept C2776818218 @default.
• W4387477568 hasConcept C2777055891 @default.
• W4387477568 hasConcept C2777341932 @default.
• W4387477568 hasConcept C2778165595 @default.
• W4387477568 hasConcept C2778186239 @default.
• W4387477568 hasConcept C2778619729 @default.
• W4387477568 hasConcept C42219234 @default.
• W4387477568 hasConcept C522805319 @default.
• W4387477568 hasConcept C71924100 @default.
• W4387477568 hasConceptScore W4387477568C118552586 @default.
• W4387477568 hasConceptScore W4387477568C126322002 @default.
• W4387477568 hasConceptScore W4387477568C129692064 @default.
• W4387477568 hasConceptScore W4387477568C161941745 @default.
• W4387477568 hasConceptScore W4387477568C164705383 @default.
• W4387477568 hasConceptScore W4387477568C177713679 @default.
• W4387477568 hasConceptScore W4387477568C194828623 @default.
• W4387477568 hasConceptScore W4387477568C2776296500 @default.
• W4387477568 hasConceptScore W4387477568C2776376669 @default.
• W4387477568 hasConceptScore W4387477568C2776818218 @default.
• W4387477568 hasConceptScore W4387477568C2777055891 @default.
• W4387477568 hasConceptScore W4387477568C2777341932 @default.
• W4387477568 hasConceptScore W4387477568C2778165595 @default.
• W4387477568 hasConceptScore W4387477568C2778186239 @default.
• W4387477568 hasConceptScore W4387477568C2778619729 @default.
• W4387477568 hasConceptScore W4387477568C42219234 @default.
• W4387477568 hasConceptScore W4387477568C522805319 @default.
• W4387477568 hasConceptScore W4387477568C71924100 @default.
• W4387477568 hasLocation W43874775681 @default.
• W4387477568 hasOpenAccess W4387477568 @default.
• W4387477568 hasPrimaryLocation W43874775681 @default.
• W4387477568 hasRelatedWork W2039671706 @default.
• W4387477568 hasRelatedWork W2052443380 @default.
• W4387477568 hasRelatedWork W2075875728 @default.
• W4387477568 hasRelatedWork W2155397218 @default.
• W4387477568 hasRelatedWork W2268236773 @default.
• W4387477568 hasRelatedWork W2979222658 @default.
• W4387477568 hasRelatedWork W2979436683 @default.
• W4387477568 hasRelatedWork W3035187661 @default.
• W4387477568 hasRelatedWork W3157550915 @default.
• W4387477568 hasRelatedWork W4210630864 @default.
• W4387477568 hasVolume "37" @default.
• W4387477568 isParatext "false" @default.
• W4387477568 isRetracted "false" @default.
• W4387477568 workType "article" @default.