FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387493206> ?p ?o ?g. }

• W4387493206 abstract "Upon subjecting molecules to nonequilibrium conditions, many biophysical and biochemical features such as molecular diffusion, protein folding, dissociation constant, as well as enzyme-catalyzed reactions can be characterized in an aqueous solution. However, conducting assays under nonequilibrium conditions in complex self-assembled biomatrices (e.g., extracellular matrices) remains challenging due to the limitations associated with sample handling, reaction design, and optical detection. Herein, we present the investigation of biomolecular thermodiffusion in noncovalently assembled synthetic or naturally derived hydrogels. This approach has been demonstrated with a large variety of analytes of different sizes across the nanoscale, including small molecules, polysaccharides, proteins, DNA, and five DNA origamis of different geometries in various polymer networks. As the aggregation of analytes can be suppressed, the in-biomatrix method has also shown advantages over in-solution measurements. Remarkably, the method provides a unique opportunity to study how a thermophoretic movement of matrix surroundings can impact the thermophoretic movement of analytes, with dimensions from low to high nm and a million-fold variation in mass. Most importantly, the method is capable of measuring binding affinity in biomatrices, allowing for characterizing the protein–ligand interaction within a more biologically relevant context." @default.
• W4387493206 created "2023-10-11" @default.
• W4387493206 creator A5018171123 @default.
• W4387493206 creator A5024467385 @default.
• W4387493206 creator A5042376015 @default.
• W4387493206 creator A5046339629 @default.
• W4387493206 creator A5054394172 @default.
• W4387493206 creator A5065867809 @default.
• W4387493206 creator A5066344717 @default.
• W4387493206 creator A5076946946 @default.
• W4387493206 creator A5077153113 @default.
• W4387493206 creator A5077832966 @default.
• W4387493206 creator A5079588531 @default.
• W4387493206 date "2023-10-10" @default.
• W4387493206 modified "2023-10-12" @default.
• W4387493206 title "Thermophoretic Analysis of Biomolecules across the Nanoscales in Self-Assembled Polymeric Matrices" @default.
• W4387493206 cites W1597994956 @default.
• W4387493206 cites W1965498876 @default.
• W4387493206 cites W1999732094 @default.
• W4387493206 cites W2012760688 @default.
• W4387493206 cites W2015693061 @default.
• W4387493206 cites W2017673251 @default.
• W4387493206 cites W2019376824 @default.
• W4387493206 cites W2068981448 @default.
• W4387493206 cites W2114160655 @default.
• W4387493206 cites W2126961173 @default.
• W4387493206 cites W2139004599 @default.
• W4387493206 cites W2146103350 @default.
• W4387493206 cites W2159877405 @default.
• W4387493206 cites W2163930707 @default.
• W4387493206 cites W2166721734 @default.
• W4387493206 cites W2319679416 @default.
• W4387493206 cites W2331558157 @default.
• W4387493206 cites W2799593323 @default.
• W4387493206 cites W2888205889 @default.
• W4387493206 cites W2914907359 @default.
• W4387493206 cites W2917476560 @default.
• W4387493206 cites W3009575153 @default.
• W4387493206 cites W3101064457 @default.
• W4387493206 cites W3135565745 @default.
• W4387493206 cites W3136674739 @default.
• W4387493206 cites W3207443835 @default.
• W4387493206 cites W4205184721 @default.
• W4387493206 cites W4220944935 @default.
• W4387493206 cites W4225123068 @default.
• W4387493206 cites W4242873557 @default.
• W4387493206 cites W4245375790 @default.
• W4387493206 cites W4362458490 @default.
• W4387493206 cites W4368355869 @default.
• W4387493206 doi "https://doi.org/10.1021/acsanm.3c03623" @default.
• W4387493206 hasPublicationYear "2023" @default.
• W4387493206 type Work @default.
• W4387493206 citedByCount "0" @default.
• W4387493206 crossrefType "journal-article" @default.
• W4387493206 hasAuthorship W4387493206A5018171123 @default.
• W4387493206 hasAuthorship W4387493206A5024467385 @default.
• W4387493206 hasAuthorship W4387493206A5042376015 @default.
• W4387493206 hasAuthorship W4387493206A5046339629 @default.
• W4387493206 hasAuthorship W4387493206A5054394172 @default.
• W4387493206 hasAuthorship W4387493206A5065867809 @default.
• W4387493206 hasAuthorship W4387493206A5066344717 @default.
• W4387493206 hasAuthorship W4387493206A5076946946 @default.
• W4387493206 hasAuthorship W4387493206A5077153113 @default.
• W4387493206 hasAuthorship W4387493206A5077832966 @default.
• W4387493206 hasAuthorship W4387493206A5079588531 @default.
• W4387493206 hasConcept C10390740 @default.
• W4387493206 hasConcept C108586683 @default.
• W4387493206 hasConcept C151730666 @default.
• W4387493206 hasConcept C171250308 @default.
• W4387493206 hasConcept C178790620 @default.
• W4387493206 hasConcept C185592680 @default.
• W4387493206 hasConcept C192562407 @default.
• W4387493206 hasConcept C2779343474 @default.
• W4387493206 hasConcept C32909587 @default.
• W4387493206 hasConcept C43617362 @default.
• W4387493206 hasConcept C49853544 @default.
• W4387493206 hasConcept C521977710 @default.
• W4387493206 hasConcept C86803240 @default.
• W4387493206 hasConceptScore W4387493206C10390740 @default.
• W4387493206 hasConceptScore W4387493206C108586683 @default.
• W4387493206 hasConceptScore W4387493206C151730666 @default.
• W4387493206 hasConceptScore W4387493206C171250308 @default.
• W4387493206 hasConceptScore W4387493206C178790620 @default.
• W4387493206 hasConceptScore W4387493206C185592680 @default.
• W4387493206 hasConceptScore W4387493206C192562407 @default.
• W4387493206 hasConceptScore W4387493206C2779343474 @default.
• W4387493206 hasConceptScore W4387493206C32909587 @default.
• W4387493206 hasConceptScore W4387493206C43617362 @default.
• W4387493206 hasConceptScore W4387493206C49853544 @default.
• W4387493206 hasConceptScore W4387493206C521977710 @default.
• W4387493206 hasConceptScore W4387493206C86803240 @default.
• W4387493206 hasFunder F4320321114 @default.
• W4387493206 hasLocation W43874932061 @default.
• W4387493206 hasOpenAccess W4387493206 @default.
• W4387493206 hasPrimaryLocation W43874932061 @default.
• W4387493206 hasRelatedWork W1944150046 @default.
• W4387493206 hasRelatedWork W2038809418 @default.
• W4387493206 hasRelatedWork W2042102689 @default.
• W4387493206 hasRelatedWork W2100501295 @default.
• W4387493206 hasRelatedWork W2277257395 @default.

• next