Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387494911> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W4387494911 endingPage "167" @default.
- W4387494911 startingPage "164" @default.
- W4387494911 abstract "The bivalent chemical cholera vaccine is the only drug for the prevention of cholera registered in the Russian Federation. The vaccine has been produced in glass bottles containing 210 tablets. At the same time, modern trends dictate the need to produce the drug in varying dispensing and more practical packaging for the convenience of the consumer. The aim of the work was to study the stability of the properties of the immunobiological medicinal product “Bivalent chemical cholera vaccine” with modified filling and in new primary packaging. Materials and methods. When studying the quality of bivalent chemical cholera vaccine batches, physicochemical parameters, formaldehyde content, specific activity and safety, abnormal toxicity, immunogenicity, and microbiological purity were assessed. Stability in terms of “specific activity” was evaluated using dot immunoassay. Results and discussion. As a result of this work, the use of several dispensing options and new primary packaging of cholera vaccine has been experimentally substantiated. The stability of the finished vaccine preparation has been established in the “accelerated aging” test and during long-term storage. The possibility of using dot immunoassay with a conjugate based on staphylococcal protein A, labeled with colloidal gold, to monitor the stability of cholera vaccine has been experimentally demonstrated." @default.
- W4387494911 created "2023-10-11" @default.
- W4387494911 creator A5024336474 @default.
- W4387494911 creator A5024710801 @default.
- W4387494911 creator A5031743650 @default.
- W4387494911 creator A5031792038 @default.
- W4387494911 creator A5033968686 @default.
- W4387494911 creator A5036385255 @default.
- W4387494911 creator A5061612191 @default.
- W4387494911 creator A5063750612 @default.
- W4387494911 creator A5086184498 @default.
- W4387494911 creator A5086848621 @default.
- W4387494911 creator A5087203722 @default.
- W4387494911 date "2023-10-09" @default.
- W4387494911 modified "2023-10-12" @default.
- W4387494911 title "Assessment of Stability of Chemical Cholera Vaccine in a New Primary Packaging" @default.
- W4387494911 cites W2908473213 @default.
- W4387494911 cites W2916468850 @default.
- W4387494911 cites W3134802153 @default.
- W4387494911 cites W4368376483 @default.
- W4387494911 doi "https://doi.org/10.21055/0370-1069-2023-3-164-167" @default.
- W4387494911 hasPublicationYear "2023" @default.
- W4387494911 type Work @default.
- W4387494911 citedByCount "0" @default.
- W4387494911 crossrefType "journal-article" @default.
- W4387494911 hasAuthorship W4387494911A5024336474 @default.
- W4387494911 hasAuthorship W4387494911A5024710801 @default.
- W4387494911 hasAuthorship W4387494911A5031743650 @default.
- W4387494911 hasAuthorship W4387494911A5031792038 @default.
- W4387494911 hasAuthorship W4387494911A5033968686 @default.
- W4387494911 hasAuthorship W4387494911A5036385255 @default.
- W4387494911 hasAuthorship W4387494911A5061612191 @default.
- W4387494911 hasAuthorship W4387494911A5063750612 @default.
- W4387494911 hasAuthorship W4387494911A5086184498 @default.
- W4387494911 hasAuthorship W4387494911A5086848621 @default.
- W4387494911 hasAuthorship W4387494911A5087203722 @default.
- W4387494911 hasBestOaLocation W43874949111 @default.
- W4387494911 hasConcept C147483822 @default.
- W4387494911 hasConcept C159047783 @default.
- W4387494911 hasConcept C185592680 @default.
- W4387494911 hasConcept C192562407 @default.
- W4387494911 hasConcept C203014093 @default.
- W4387494911 hasConcept C2777047711 @default.
- W4387494911 hasConcept C2778643871 @default.
- W4387494911 hasConcept C2780722889 @default.
- W4387494911 hasConcept C2780868878 @default.
- W4387494911 hasConcept C523546767 @default.
- W4387494911 hasConcept C54355233 @default.
- W4387494911 hasConcept C71924100 @default.
- W4387494911 hasConcept C86803240 @default.
- W4387494911 hasConceptScore W4387494911C147483822 @default.
- W4387494911 hasConceptScore W4387494911C159047783 @default.
- W4387494911 hasConceptScore W4387494911C185592680 @default.
- W4387494911 hasConceptScore W4387494911C192562407 @default.
- W4387494911 hasConceptScore W4387494911C203014093 @default.
- W4387494911 hasConceptScore W4387494911C2777047711 @default.
- W4387494911 hasConceptScore W4387494911C2778643871 @default.
- W4387494911 hasConceptScore W4387494911C2780722889 @default.
- W4387494911 hasConceptScore W4387494911C2780868878 @default.
- W4387494911 hasConceptScore W4387494911C523546767 @default.
- W4387494911 hasConceptScore W4387494911C54355233 @default.
- W4387494911 hasConceptScore W4387494911C71924100 @default.
- W4387494911 hasConceptScore W4387494911C86803240 @default.
- W4387494911 hasIssue "3" @default.
- W4387494911 hasLocation W43874949111 @default.
- W4387494911 hasOpenAccess W4387494911 @default.
- W4387494911 hasPrimaryLocation W43874949111 @default.
- W4387494911 hasRelatedWork W1972012687 @default.
- W4387494911 hasRelatedWork W2008019436 @default.
- W4387494911 hasRelatedWork W2063979677 @default.
- W4387494911 hasRelatedWork W2141579433 @default.
- W4387494911 hasRelatedWork W2312158452 @default.
- W4387494911 hasRelatedWork W2412000071 @default.
- W4387494911 hasRelatedWork W2899084033 @default.
- W4387494911 hasRelatedWork W4247103150 @default.
- W4387494911 hasRelatedWork W4254991728 @default.
- W4387494911 hasRelatedWork W4366372159 @default.
- W4387494911 isParatext "false" @default.
- W4387494911 isRetracted "false" @default.
- W4387494911 workType "article" @default.