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• W4387496462 abstract "Recent evidence suggests that the timing of introduction, types, and amounts of complementary foods/allergenic foods may influence the risk of allergic disease. However, the evidence has not been updated and comprehensively synthesized. The Cochrane Library, EMBASE, Web of Science, and PubMed databases were searched from the inception of each database up to May 31, 2023 (articles prior to 2000 were excluded manually). Statistical analyses were performed using RevMan 5. The GRADE approach was followed to rate the certainty of evidence. This study was registered with PROSPERO, CRD42022379264. Compared to > 6 months, early introduction of eggs (≤6 months of age) might reduce the risk of food allergies in preschoolers aged < 6 years (OR, 0.65; 95%CI, 0.53–0.81), but had no effect on asthma or atopic dermatitis (AD). Consumption of fish at 6–12 months might reduce the risk of asthma in children (aged 5–17 years) compared to late introduction after 12 months (OR, 0.61; 95%CI, 0.52–0.72). Introduction of allergenic foods for ≤ 6 months of age, compared to > 6 months, was a protective factor for the future risk (children aged ≤ 10 years) of AD (OR, 0.93; 95%CI, 0.89–0.97). Probiotic intervention for infants at high risk of allergic disease significantly reduced the risk of food allergy at ages 0–3 years (OR, 0.72; 95%CI, 0.56–0.94), asthma at aged 6–12 years (OR, 0.61; 95%CI, 0.41–0.90), and AD at aged < 6 years (3–6 years: OR, 0.70; 95%CI, 0.52–0.94; 0–3 years: OR, 0.73; 95%CI, 0.59–0.91). Early introduction of complementary foods or the high-dose vitamin D supplementation in infancy was not associated with the risk of developing food allergies, asthma, or AD during childhood. Early introduction to potential allergen foods for normal infants or probiotics for infants at high risk of allergies may protect against development of allergic disease." @default.
• W4387496462 created "2023-10-11" @default.
• W4387496462 creator A5013016254 @default.
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• W4387496462 date "2023-10-01" @default.
• W4387496462 modified "2023-10-14" @default.
• W4387496462 title "Effects of early diet on the prevalence of allergic disease in children: A systematic review and meta-analysis" @default.
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