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- W4387496719 endingPage "4920" @default.
- W4387496719 startingPage "4920" @default.
- W4387496719 abstract "Brain cancer is known as one of the deadliest cancers globally. One of the causative factors is the imbalance between oxidative and antioxidant activities in the body, which is referred to as oxidative stress (OS). As part of regular metabolism, oxygen is reduced by electrons, resulting in the creation of numerous reactive oxygen species (ROS). Inflammation is intricately associated with the generation of OS, leading to the increased production and accumulation of reactive oxygen and nitrogen species (RONS). Glioma stands out as one of the most common malignant tumors affecting the central nervous system (CNS), characterized by changes in the redox balance. Brain cancer cells exhibit inherent resistance to most conventional treatments, primarily due to the distinctive tumor microenvironment. Oxidative stress (OS) plays a crucial role in the development of various brain-related malignancies, such as glioblastoma multiforme (GBM) and medulloblastoma, where OS significantly disrupts the normal homeostasis of the brain. In this review, we provide in-depth descriptions of prospective targets and therapeutics, along with an assessment of OS and its impact on brain cancer metabolism. We also discuss targeted therapies." @default.
- W4387496719 created "2023-10-11" @default.
- W4387496719 creator A5016579839 @default.
- W4387496719 creator A5027859418 @default.
- W4387496719 creator A5058837826 @default.
- W4387496719 date "2023-10-10" @default.
- W4387496719 modified "2023-10-12" @default.
- W4387496719 title "Role of Oxidative Stress in Metabolic Reprogramming of Brain Cancer" @default.
- W4387496719 cites W1548745956 @default.
- W4387496719 cites W1636387298 @default.
- W4387496719 cites W1821918060 @default.
- W4387496719 cites W1905538010 @default.
- W4387496719 cites W1983937216 @default.
- W4387496719 cites W1997023449 @default.
- W4387496719 cites W2001305887 @default.
- W4387496719 cites W2002490462 @default.
- W4387496719 cites W2002825673 @default.
- W4387496719 cites W2008421820 @default.
- W4387496719 cites W2013322023 @default.
- W4387496719 cites W2021787243 @default.
- W4387496719 cites W2024235550 @default.
- W4387496719 cites W2033958147 @default.
- W4387496719 cites W2038900982 @default.
- W4387496719 cites W2045711626 @default.
- W4387496719 cites W2049315573 @default.
- W4387496719 cites W2054087224 @default.
- W4387496719 cites W2054149900 @default.
- W4387496719 cites W2057622179 @default.
- W4387496719 cites W2064327102 @default.
- W4387496719 cites W2066385938 @default.
- W4387496719 cites W2072755009 @default.
- W4387496719 cites W2074561212 @default.
- W4387496719 cites W2078586973 @default.
- W4387496719 cites W2089439333 @default.
- W4387496719 cites W2096287682 @default.
- W4387496719 cites W2097951502 @default.
- W4387496719 cites W2100566062 @default.
- W4387496719 cites W2104962692 @default.
- W4387496719 cites W2105164395 @default.
- W4387496719 cites W2113012900 @default.
- W4387496719 cites W2121113421 @default.
- W4387496719 cites W2122816851 @default.
- W4387496719 cites W2125642839 @default.
- W4387496719 cites W2133610610 @default.
- W4387496719 cites W2139665512 @default.
- W4387496719 cites W2140442678 @default.
- W4387496719 cites W2140525205 @default.
- W4387496719 cites W2163458899 @default.
- W4387496719 cites W2168174626 @default.
- W4387496719 cites W2170488331 @default.
- W4387496719 cites W2281758534 @default.
- W4387496719 cites W2309772277 @default.
- W4387496719 cites W2318271015 @default.
- W4387496719 cites W2340180600 @default.
- W4387496719 cites W2366536035 @default.
- W4387496719 cites W2415945663 @default.
- W4387496719 cites W2419457711 @default.
- W4387496719 cites W2469761909 @default.
- W4387496719 cites W2480120367 @default.
- W4387496719 cites W2492207739 @default.
- W4387496719 cites W2499454019 @default.
- W4387496719 cites W2520593336 @default.
- W4387496719 cites W2605570305 @default.
- W4387496719 cites W2606811642 @default.
- W4387496719 cites W2691753618 @default.
- W4387496719 cites W2769622412 @default.
- W4387496719 cites W2780575142 @default.
- W4387496719 cites W2790035192 @default.
- W4387496719 cites W2791703405 @default.
- W4387496719 cites W2797862264 @default.
- W4387496719 cites W2799986334 @default.
- W4387496719 cites W2906120852 @default.
- W4387496719 cites W2907510643 @default.
- W4387496719 cites W2909817598 @default.
- W4387496719 cites W2914084793 @default.
- W4387496719 cites W2937074474 @default.
- W4387496719 cites W2942814044 @default.
- W4387496719 cites W2947314472 @default.
- W4387496719 cites W2979415304 @default.
- W4387496719 cites W2991148119 @default.
- W4387496719 cites W2991718894 @default.
- W4387496719 cites W3011304091 @default.
- W4387496719 cites W3011321509 @default.
- W4387496719 cites W3015150584 @default.
- W4387496719 cites W3049253240 @default.
- W4387496719 cites W3080964358 @default.
- W4387496719 cites W3108585785 @default.
- W4387496719 cites W3121741001 @default.
- W4387496719 cites W3122294405 @default.
- W4387496719 cites W3131336791 @default.
- W4387496719 cites W3136173423 @default.
- W4387496719 cites W3137717232 @default.
- W4387496719 cites W3142067702 @default.
- W4387496719 cites W3153831334 @default.
- W4387496719 cites W3153860689 @default.
- W4387496719 cites W3164578373 @default.
- W4387496719 cites W3165913615 @default.
- W4387496719 cites W3183953302 @default.