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• W4387520003 abstract "Invasive meningococcal disease (IMD) cases declined upon the implementation of non-pharmaceutical measures to control the COVID-19 pandemic. A rebound in IMD cases was feared upon easing these measures. We conducted a retrospective descriptive study using the French National Reference Centre Database for meningococci between 2015-2022. We scored serogroups, sex, age groups, and clonal complexes of the corresponding isolates. Our data clearly show a decline in the number of IMD cases for all serogroups and age groups until 2021. This decline was mainly due to a decrease in IMD cases provoked by the hyperinvasive ST-11 clonal complex. However, since the fall of 2021, there has been an increase in IMD cases, which accelerated in the second half of 2022. This rebound concerned all age groups, in particular 16-24 years. The increase in cases due to serogroups B, W, and Y were mainly due to the expansion of isolates of the ST-7460, the clonal complex ST-9316 strains and the clonal complex ST-23, respectively. IMD epidemiology changes constantly and profound epidemiological changes have been recently observed. The surveillance of IMD needs to be enhanced using molecular tools. Additionally, vaccination strategies need to be updated to acknowledge recent epidemiological changes of these vaccine-preventable serogroups." @default.
• W4387520003 created "2023-10-12" @default.
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• W4387520003 date "2023-10-01" @default.
• W4387520003 modified "2023-10-12" @default.
• W4387520003 title "The rapid rebound of invasive meningococcal disease in France at the end of 2022" @default.
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• W4387520003 doi "https://doi.org/10.1016/j.jiph.2023.10.001" @default.
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