FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387530004> ?p ?o ?g. }

• W4387530004 abstract "ABSTRACT Echovirus 5 (E5) belongs to the enterovirus B (EV-B) species, which is one of the pathogens causing respiratory diseases. Only two whole genome sequences (WGSs) of E5 are available in GenBank, and few studies on E5 have been reported worldwide. In this study, human rhabdomyosarcoma (RD) cells were used to isolate E5 from respiratory samples associated with severe acute respiratory infection (SARI). The nucleotide sequence of the VP1 region and the WGSs of two E5 strains were sequenced using Sanger sequencing and high-throughput sequencing technology, respectively. Together with 31 E5 VP1 sequences and 2 WGSs downloaded from GenBank, a total of 33 complete VP1 sequences and 4 WGSs were used for genetic characterization and evolutionary analysis. Phylogenetic analysis revealed five genotypes (A–E) based on complete VP1 sequences. Evolutionary analysis showed that the time to the most recent common ancestor of E5 was approximately 1952 (95% highest posterior density [HPD] range, 1948–1953]), with a mean substitution rate of 7.74 × 10 −3 subs/site/year (95% HPD range, 6.44–9.11 × 10 −3 ). In addition, the WGS analyses showed that the nucleotide and amino acid similarities of the coding regions of the two strains obtained in this study with the prototype of the E5 strain Noyce were 80.2% and 97.2%, respectively. Recombination analysis showed that the two E5 strains may have intraspecific recombination with E6, EV-B85, and CVA9 serotypes in the nonstructural region. This study reports the isolation of E5 from SARI cases for the first time, and genetic characterization and evolutionary analysis provide valuable information on global E5 molecular epidemiology. IMPORTANCE This study is the first report of echovirus 5 (E5) associated with severe acute respiratory infection and obtained the first E5 whole-genome sequence in China. Combined with the sequences available in the GenBank database, the first genotyping, phylogenetic characteristics, recombination, and genetic evolutionary analysis of E5 was performed in this study. Our findings providing valuable information on global E5 molecular epidemiology." @default.
• W4387530004 created "2023-10-12" @default.
• W4387530004 creator A5021248802 @default.
• W4387530004 creator A5023084225 @default.
• W4387530004 creator A5053748274 @default.
• W4387530004 creator A5059389072 @default.
• W4387530004 creator A5064222660 @default.
• W4387530004 creator A5064453660 @default.
• W4387530004 creator A5068107262 @default.
• W4387530004 creator A5084803961 @default.
• W4387530004 creator A5087227510 @default.
• W4387530004 date "2023-10-11" @default.
• W4387530004 modified "2023-10-13" @default.
• W4387530004 title "Phylogenetic characteristics and recombination analysis of echovirus 5 associated with severe acute respiratory infection in China" @default.
• W4387530004 cites W1674554014 @default.
• W4387530004 cites W1828335005 @default.
• W4387530004 cites W1969042907 @default.
• W4387530004 cites W1975237415 @default.
• W4387530004 cites W1978130471 @default.
• W4387530004 cites W1996050650 @default.
• W4387530004 cites W1999708869 @default.
• W4387530004 cites W2018117375 @default.
• W4387530004 cites W2022044075 @default.
• W4387530004 cites W2023714135 @default.
• W4387530004 cites W2041616862 @default.
• W4387530004 cites W2073999011 @default.
• W4387530004 cites W2076296347 @default.
• W4387530004 cites W2107500874 @default.
• W4387530004 cites W2113806528 @default.
• W4387530004 cites W2123753779 @default.
• W4387530004 cites W2132936904 @default.
• W4387530004 cites W2141972743 @default.
• W4387530004 cites W2142196041 @default.
• W4387530004 cites W2156072954 @default.
• W4387530004 cites W2160378127 @default.
• W4387530004 cites W2162318638 @default.
• W4387530004 cites W2311203695 @default.
• W4387530004 cites W2322358787 @default.
• W4387530004 cites W2755331695 @default.
• W4387530004 cites W2766806426 @default.
• W4387530004 cites W2793461621 @default.
• W4387530004 cites W2793719328 @default.
• W4387530004 cites W2807308836 @default.
• W4387530004 cites W2888081564 @default.
• W4387530004 cites W2891030861 @default.
• W4387530004 cites W2903041908 @default.
• W4387530004 cites W3003830226 @default.
• W4387530004 cites W3088384064 @default.
• W4387530004 cites W3162383969 @default.
• W4387530004 cites W3198814643 @default.
• W4387530004 cites W4224287786 @default.
• W4387530004 cites W4225685299 @default.
• W4387530004 cites W4226237082 @default.
• W4387530004 doi "https://doi.org/10.1128/spectrum.01711-23" @default.
• W4387530004 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37819138" @default.
• W4387530004 hasPublicationYear "2023" @default.
• W4387530004 type Work @default.
• W4387530004 citedByCount "0" @default.
• W4387530004 crossrefType "journal-article" @default.
• W4387530004 hasAuthorship W4387530004A5021248802 @default.
• W4387530004 hasAuthorship W4387530004A5023084225 @default.
• W4387530004 hasAuthorship W4387530004A5053748274 @default.
• W4387530004 hasAuthorship W4387530004A5059389072 @default.
• W4387530004 hasAuthorship W4387530004A5064222660 @default.
• W4387530004 hasAuthorship W4387530004A5064453660 @default.
• W4387530004 hasAuthorship W4387530004A5068107262 @default.
• W4387530004 hasAuthorship W4387530004A5084803961 @default.
• W4387530004 hasAuthorship W4387530004A5087227510 @default.
• W4387530004 hasBestOaLocation W43875300041 @default.
• W4387530004 hasConcept C104317684 @default.
• W4387530004 hasConcept C105702510 @default.
• W4387530004 hasConcept C135763542 @default.
• W4387530004 hasConcept C159047783 @default.
• W4387530004 hasConcept C193252679 @default.
• W4387530004 hasConcept C2522874641 @default.
• W4387530004 hasConcept C2777888124 @default.
• W4387530004 hasConcept C2778819740 @default.
• W4387530004 hasConcept C2993183539 @default.
• W4387530004 hasConcept C51679486 @default.
• W4387530004 hasConcept C534529494 @default.
• W4387530004 hasConcept C54355233 @default.
• W4387530004 hasConcept C61053724 @default.
• W4387530004 hasConcept C76818968 @default.
• W4387530004 hasConcept C79029880 @default.
• W4387530004 hasConcept C86803240 @default.
• W4387530004 hasConceptScore W4387530004C104317684 @default.
• W4387530004 hasConceptScore W4387530004C105702510 @default.
• W4387530004 hasConceptScore W4387530004C135763542 @default.
• W4387530004 hasConceptScore W4387530004C159047783 @default.
• W4387530004 hasConceptScore W4387530004C193252679 @default.
• W4387530004 hasConceptScore W4387530004C2522874641 @default.
• W4387530004 hasConceptScore W4387530004C2777888124 @default.
• W4387530004 hasConceptScore W4387530004C2778819740 @default.
• W4387530004 hasConceptScore W4387530004C2993183539 @default.
• W4387530004 hasConceptScore W4387530004C51679486 @default.
• W4387530004 hasConceptScore W4387530004C534529494 @default.
• W4387530004 hasConceptScore W4387530004C54355233 @default.
• W4387530004 hasConceptScore W4387530004C61053724 @default.
• W4387530004 hasConceptScore W4387530004C76818968 @default.
• W4387530004 hasConceptScore W4387530004C79029880 @default.

• next