Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387542917> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W4387542917 endingPage "18" @default.
- W4387542917 startingPage "13" @default.
- W4387542917 abstract "Apixaban is a direct oral anticoagulation agent that exerts its effect through the direct inhibition of factor Xa. We treated a case of massive intoxication with 70 tablets of apixaban and have presented the clinical course of the associated anti-Xa activities. A 49-year-old woman was admitted to the emergency department approximately 1.5 h after impulsive self-intoxication with 175 mg of apixaban. She developed coagulopathy with prothrombin time-international normalized ratio (PT-INR) of 3.65, activated partial thromboplastin time of 56.5 s, and antithrombin activity (AT) of >150% (at 1.5 h post-ingestion). The patient’s initial and peak anti-Xa activity was 17.7 IU/mL, and its elimination displayed first-order kinetics with a half-life of 10.5 h. The patient’s anti-Xa activity was within the therapeutic dose range at 26 h post-ingestion, and she recovered without experiencing any bleeding complications. Her coagulopathy also returned to normal level at the same timing. This result suggests that PT-INR and AT can be used as substitute markers of overwhelmed anticoagulation following massive overdose of apixaban. A case of apixaban overdose with associated anti-Xa activities was presented. There was favorable resolution of anticoagulation without specific treatments." @default.
- W4387542917 created "2023-10-12" @default.
- W4387542917 creator A5026879845 @default.
- W4387542917 creator A5028404716 @default.
- W4387542917 creator A5039303517 @default.
- W4387542917 creator A5050818867 @default.
- W4387542917 creator A5054922933 @default.
- W4387542917 creator A5061504970 @default.
- W4387542917 creator A5064311540 @default.
- W4387542917 creator A5075638468 @default.
- W4387542917 date "2023-09-12" @default.
- W4387542917 modified "2023-10-12" @default.
- W4387542917 title "Massive Intoxication with 70 Tablets of Apixaban: A Case Report" @default.
- W4387542917 cites W1568662837 @default.
- W4387542917 cites W2029696469 @default.
- W4387542917 cites W2499425223 @default.
- W4387542917 cites W2553226143 @default.
- W4387542917 cites W2581456358 @default.
- W4387542917 cites W2763636556 @default.
- W4387542917 cites W2769760280 @default.
- W4387542917 cites W2794176556 @default.
- W4387542917 cites W2901170960 @default.
- W4387542917 cites W2914381505 @default.
- W4387542917 doi "https://doi.org/10.1159/000533520" @default.
- W4387542917 hasPublicationYear "2023" @default.
- W4387542917 type Work @default.
- W4387542917 citedByCount "0" @default.
- W4387542917 crossrefType "journal-article" @default.
- W4387542917 hasAuthorship W4387542917A5026879845 @default.
- W4387542917 hasAuthorship W4387542917A5028404716 @default.
- W4387542917 hasAuthorship W4387542917A5039303517 @default.
- W4387542917 hasAuthorship W4387542917A5050818867 @default.
- W4387542917 hasAuthorship W4387542917A5054922933 @default.
- W4387542917 hasAuthorship W4387542917A5061504970 @default.
- W4387542917 hasAuthorship W4387542917A5064311540 @default.
- W4387542917 hasAuthorship W4387542917A5075638468 @default.
- W4387542917 hasBestOaLocation W43875429171 @default.
- W4387542917 hasConcept C126322002 @default.
- W4387542917 hasConcept C2776301958 @default.
- W4387542917 hasConcept C2777091921 @default.
- W4387542917 hasConcept C2777557582 @default.
- W4387542917 hasConcept C2778261982 @default.
- W4387542917 hasConcept C2778382381 @default.
- W4387542917 hasConcept C2778661090 @default.
- W4387542917 hasConcept C2779026020 @default.
- W4387542917 hasConcept C2779161974 @default.
- W4387542917 hasConcept C2779936836 @default.
- W4387542917 hasConcept C2780434524 @default.
- W4387542917 hasConcept C2780638905 @default.
- W4387542917 hasConcept C42219234 @default.
- W4387542917 hasConcept C71924100 @default.
- W4387542917 hasConceptScore W4387542917C126322002 @default.
- W4387542917 hasConceptScore W4387542917C2776301958 @default.
- W4387542917 hasConceptScore W4387542917C2777091921 @default.
- W4387542917 hasConceptScore W4387542917C2777557582 @default.
- W4387542917 hasConceptScore W4387542917C2778261982 @default.
- W4387542917 hasConceptScore W4387542917C2778382381 @default.
- W4387542917 hasConceptScore W4387542917C2778661090 @default.
- W4387542917 hasConceptScore W4387542917C2779026020 @default.
- W4387542917 hasConceptScore W4387542917C2779161974 @default.
- W4387542917 hasConceptScore W4387542917C2779936836 @default.
- W4387542917 hasConceptScore W4387542917C2780434524 @default.
- W4387542917 hasConceptScore W4387542917C2780638905 @default.
- W4387542917 hasConceptScore W4387542917C42219234 @default.
- W4387542917 hasConceptScore W4387542917C71924100 @default.
- W4387542917 hasLocation W43875429171 @default.
- W4387542917 hasOpenAccess W4387542917 @default.
- W4387542917 hasPrimaryLocation W43875429171 @default.
- W4387542917 hasRelatedWork W1857288271 @default.
- W4387542917 hasRelatedWork W1972266366 @default.
- W4387542917 hasRelatedWork W2029341269 @default.
- W4387542917 hasRelatedWork W2035952571 @default.
- W4387542917 hasRelatedWork W2110223924 @default.
- W4387542917 hasRelatedWork W2128846056 @default.
- W4387542917 hasRelatedWork W2326821580 @default.
- W4387542917 hasRelatedWork W2359135438 @default.
- W4387542917 hasRelatedWork W2811413127 @default.
- W4387542917 hasRelatedWork W4211117411 @default.
- W4387542917 isParatext "false" @default.
- W4387542917 isRetracted "false" @default.
- W4387542917 workType "article" @default.