Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387563058> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W4387563058 abstract "Individuals with autoimmune Addison's disease (AAD) take replacement medication for the lack of adrenal-derived glucocorticoid and mineralocorticoid hormones from diagnosis. The brain is highly sensitive to these hormones, but the consequence of having AAD for brain health has not been widely addressed.The present study compared resting-state functional connectivity (rs-fc) of the brain between individuals with AAD and healthy controls.Fifty-seven patients with AAD (33 females) and 69 healthy controls (39 females), aged 19-43 years were scanned with 3 T magnetic resonance imaging (MRI).Independent component and subsequent dual regression analyses revealed that individuals with AAD had stronger rs-fc compared to controls in three networks: the bilateral orbito-frontal cortex (OFC), the left medial visual- and left posterior default mode network. A higher glucocorticoid replacement dose was associated with stronger rs-fc in a small part of the left OFC in patients. We did not find any clear associations between rs-fc and executive functions or mental fatigue.Our results suggest that having AAD affects the baseline functional organization of the brain and that current treatment strategies of AAD may be one risk factor." @default.
- W4387563058 created "2023-10-13" @default.
- W4387563058 creator A5014406448 @default.
- W4387563058 creator A5034735829 @default.
- W4387563058 creator A5038991361 @default.
- W4387563058 creator A5059135870 @default.
- W4387563058 creator A5078801536 @default.
- W4387563058 creator A5078951244 @default.
- W4387563058 date "2023-10-11" @default.
- W4387563058 modified "2023-10-13" @default.
- W4387563058 title "Increased resting-state functional connectivity in patients with autoimmune Addison’s disease" @default.
- W4387563058 doi "https://doi.org/10.1210/clinem/dgad592" @default.
- W4387563058 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37820745" @default.
- W4387563058 hasPublicationYear "2023" @default.
- W4387563058 type Work @default.
- W4387563058 citedByCount "0" @default.
- W4387563058 crossrefType "journal-article" @default.
- W4387563058 hasAuthorship W4387563058A5014406448 @default.
- W4387563058 hasAuthorship W4387563058A5034735829 @default.
- W4387563058 hasAuthorship W4387563058A5038991361 @default.
- W4387563058 hasAuthorship W4387563058A5059135870 @default.
- W4387563058 hasAuthorship W4387563058A5078801536 @default.
- W4387563058 hasAuthorship W4387563058A5078951244 @default.
- W4387563058 hasBestOaLocation W43875630581 @default.
- W4387563058 hasConcept C126322002 @default.
- W4387563058 hasConcept C126838900 @default.
- W4387563058 hasConcept C134018914 @default.
- W4387563058 hasConcept C141516989 @default.
- W4387563058 hasConcept C143409427 @default.
- W4387563058 hasConcept C15744967 @default.
- W4387563058 hasConcept C169760540 @default.
- W4387563058 hasConcept C2776069600 @default.
- W4387563058 hasConcept C2779134260 @default.
- W4387563058 hasConcept C2779226451 @default.
- W4387563058 hasConcept C2780841215 @default.
- W4387563058 hasConcept C3018011982 @default.
- W4387563058 hasConcept C66324658 @default.
- W4387563058 hasConcept C71315377 @default.
- W4387563058 hasConcept C71924100 @default.
- W4387563058 hasConceptScore W4387563058C126322002 @default.
- W4387563058 hasConceptScore W4387563058C126838900 @default.
- W4387563058 hasConceptScore W4387563058C134018914 @default.
- W4387563058 hasConceptScore W4387563058C141516989 @default.
- W4387563058 hasConceptScore W4387563058C143409427 @default.
- W4387563058 hasConceptScore W4387563058C15744967 @default.
- W4387563058 hasConceptScore W4387563058C169760540 @default.
- W4387563058 hasConceptScore W4387563058C2776069600 @default.
- W4387563058 hasConceptScore W4387563058C2779134260 @default.
- W4387563058 hasConceptScore W4387563058C2779226451 @default.
- W4387563058 hasConceptScore W4387563058C2780841215 @default.
- W4387563058 hasConceptScore W4387563058C3018011982 @default.
- W4387563058 hasConceptScore W4387563058C66324658 @default.
- W4387563058 hasConceptScore W4387563058C71315377 @default.
- W4387563058 hasConceptScore W4387563058C71924100 @default.
- W4387563058 hasLocation W43875630581 @default.
- W4387563058 hasLocation W43875630582 @default.
- W4387563058 hasOpenAccess W4387563058 @default.
- W4387563058 hasPrimaryLocation W43875630581 @default.
- W4387563058 hasRelatedWork W1520477417 @default.
- W4387563058 hasRelatedWork W1585336261 @default.
- W4387563058 hasRelatedWork W2038307665 @default.
- W4387563058 hasRelatedWork W2075991736 @default.
- W4387563058 hasRelatedWork W2143570064 @default.
- W4387563058 hasRelatedWork W2793605638 @default.
- W4387563058 hasRelatedWork W3150454329 @default.
- W4387563058 hasRelatedWork W3205149984 @default.
- W4387563058 hasRelatedWork W4253292488 @default.
- W4387563058 hasRelatedWork W2948361065 @default.
- W4387563058 isParatext "false" @default.
- W4387563058 isRetracted "false" @default.
- W4387563058 workType "article" @default.