FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387563244> ?p ?o ?g. }

• W4387563244 abstract "The neuropathological confirmation serves as the gold standard for diagnosing Alzheimer's disease (AD), but it is usually not available to the living individuals. In addition, the gold standard for diagnosing Mild Cognitive Impairment (MCI) remains unclear yet. Neuropsychological testing, such as the Montreal Cognitive Assessment (MoCA), Mini-Mental State Examination (MMSE) and Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-cog), is commonly used tests in identifying AD and MCI, offering convenience, affordability, non-invasiveness, and accessibility in clinical settings. We aimed to accurately evaluate the discriminative ability of the three tests administrated at the same visit simultaneously in detecting AD and MCI due to AD in the absence of a gold standard.A total of 1289 participants aged over 65 were included from the baseline visits of Alzheimer's disease Neuroimaging Initiative. Bayesian latent class models, accounting for conditional dependence between MoCA and MMSE, were conducted to assess the diagnostic accuracy of the three tests for detecting AD and MCI.In detecting AD, the ADAS-cog had the highest Youden's Index (0.829), followed by the MoCA(0.813) and MMSE(0.796). The ADAS-cog and MoCA showed similar sensitivity (0.922 vs 0.912) and specificity (0.907 vs 0.901), while the MMSE had lower sensitivity (0.874) and higher specificity (0.922). For MCI detection, the ADAS-cog had the highest Youden's Index (0.704) compared to the MoCA (0.614) and MMSE (0.478). The ADAS-cog exhibited the highest sensitivity, closely followed by the MoCA and MMSE (0.869 vs 0.845 vs 0.757), and the ADAS-cog also had good specificity (0.835 vs 0.769 vs 0.721). The estimated true prevalence of AD among individuals aged over 65 was 20.0%, and the estimated true prevalence of MCI due to AD was 24.8%.The findings suggest that the ADAS-cog and MoCA are reliable tools for detecting AD and MCI, while the MMSE may be less sensitive in detecting these conditions. A large underdiagnosis of the MCI and Alzheimer's population still remains in clinical screening." @default.
• W4387563244 created "2023-10-13" @default.
• W4387563244 creator A5038688992 @default.
• W4387563244 creator A5055354898 @default.
• W4387563244 creator A5057674674 @default.
• W4387563244 creator A5065784569 @default.
• W4387563244 creator A5082676682 @default.
• W4387563244 date "2023-10-12" @default.
• W4387563244 modified "2023-10-15" @default.
• W4387563244 title "Bayesian estimation for the accuracy of three neuropsychological tests in detecting Alzheimer's disease and mild cognitive impairment: a retrospective analysis of the ADNI database" @default.
• W4387563244 cites W1531193559 @default.
• W4387563244 cites W1704947773 @default.
• W4387563244 cites W1847168837 @default.
• W4387563244 cites W1953027527 @default.
• W4387563244 cites W1968291003 @default.
• W4387563244 cites W1977168273 @default.
• W4387563244 cites W2002949133 @default.
• W4387563244 cites W2008854521 @default.
• W4387563244 cites W2028886760 @default.
• W4387563244 cites W2043020182 @default.
• W4387563244 cites W2044181079 @default.
• W4387563244 cites W2058161128 @default.
• W4387563244 cites W2068225985 @default.
• W4387563244 cites W2113708991 @default.
• W4387563244 cites W2118097904 @default.
• W4387563244 cites W2134776511 @default.
• W4387563244 cites W2148080316 @default.
• W4387563244 cites W2157961848 @default.
• W4387563244 cites W2165758561 @default.
• W4387563244 cites W2167311298 @default.
• W4387563244 cites W2195791173 @default.
• W4387563244 cites W2417024276 @default.
• W4387563244 cites W2519808874 @default.
• W4387563244 cites W2521625994 @default.
• W4387563244 cites W2555002837 @default.
• W4387563244 cites W2597839143 @default.
• W4387563244 cites W2605178010 @default.
• W4387563244 cites W2612690964 @default.
• W4387563244 cites W2790890573 @default.
• W4387563244 cites W2794316874 @default.
• W4387563244 cites W2893801790 @default.
• W4387563244 cites W2899260564 @default.
• W4387563244 cites W2907154105 @default.
• W4387563244 cites W2922493104 @default.
• W4387563244 cites W2964623449 @default.
• W4387563244 cites W2974975989 @default.
• W4387563244 cites W2980179095 @default.
• W4387563244 cites W3020417681 @default.
• W4387563244 cites W3081261157 @default.
• W4387563244 cites W3119079931 @default.
• W4387563244 cites W3124878541 @default.
• W4387563244 cites W3159530258 @default.
• W4387563244 cites W4225960529 @default.
• W4387563244 cites W4226414629 @default.
• W4387563244 cites W4235875658 @default.
• W4387563244 cites W4293012936 @default.
• W4387563244 cites W4324309277 @default.
• W4387563244 doi "https://doi.org/10.1186/s40001-023-01265-6" @default.
• W4387563244 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37821912" @default.
• W4387563244 hasPublicationYear "2023" @default.
• W4387563244 type Work @default.
• W4387563244 citedByCount "0" @default.
• W4387563244 crossrefType "journal-article" @default.
• W4387563244 hasAuthorship W4387563244A5038688992 @default.
• W4387563244 hasAuthorship W4387563244A5055354898 @default.
• W4387563244 hasAuthorship W4387563244A5057674674 @default.
• W4387563244 hasAuthorship W4387563244A5065784569 @default.
• W4387563244 hasAuthorship W4387563244A5082676682 @default.
• W4387563244 hasBestOaLocation W43875632441 @default.
• W4387563244 hasConcept C118552586 @default.
• W4387563244 hasConcept C126322002 @default.
• W4387563244 hasConcept C14216870 @default.
• W4387563244 hasConcept C15744967 @default.
• W4387563244 hasConcept C169900460 @default.
• W4387563244 hasConcept C2776632958 @default.
• W4387563244 hasConcept C2779134260 @default.
• W4387563244 hasConcept C2779483572 @default.
• W4387563244 hasConcept C2984915365 @default.
• W4387563244 hasConcept C40993552 @default.
• W4387563244 hasConcept C536788834 @default.
• W4387563244 hasConcept C548259974 @default.
• W4387563244 hasConcept C58693492 @default.
• W4387563244 hasConcept C71924100 @default.
• W4387563244 hasConceptScore W4387563244C118552586 @default.
• W4387563244 hasConceptScore W4387563244C126322002 @default.
• W4387563244 hasConceptScore W4387563244C14216870 @default.
• W4387563244 hasConceptScore W4387563244C15744967 @default.
• W4387563244 hasConceptScore W4387563244C169900460 @default.
• W4387563244 hasConceptScore W4387563244C2776632958 @default.
• W4387563244 hasConceptScore W4387563244C2779134260 @default.
• W4387563244 hasConceptScore W4387563244C2779483572 @default.
• W4387563244 hasConceptScore W4387563244C2984915365 @default.
• W4387563244 hasConceptScore W4387563244C40993552 @default.
• W4387563244 hasConceptScore W4387563244C536788834 @default.
• W4387563244 hasConceptScore W4387563244C548259974 @default.
• W4387563244 hasConceptScore W4387563244C58693492 @default.
• W4387563244 hasConceptScore W4387563244C71924100 @default.
• W4387563244 hasFunder F4320321001 @default.
• W4387563244 hasIssue "1" @default.
• W4387563244 hasLocation W43875632441 @default.

• next