Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387575958> ?p ?o ?g. }
- W4387575958 endingPage "7042" @default.
- W4387575958 startingPage "7042" @default.
- W4387575958 abstract "Licorice is a frequently applied herb with potential edible and medicinal value based on various flavonoids and triterpenes. However, studies on detailed flavonoid and triterpene metabolism and the molecular basis of their biosynthesis in licorice are very limited, especially under drought conditions. In the present study, we carried out transcriptome, proteome, and metabolome experiments. To ultimately combine three omics for analysis, we performed a bioinformatics comparison, integrating transcriptome data and proteome data through a Cloud platform, along with a simplified biosynthesis of primary flavonoids and triterpenoids in the KEGG pathway based on metabolomic results. The biosynthesis pathways of triterpenes and flavonoids are enriched at both gene and protein levels. Key flavonoid-related genes (PAL, 4CL, CHS, CHI, CYP93C, HIDH, HI4OMT, and CYP81E1_7) and representative proteins (HIDH, CYP81E1_7, CYP93C, and VR) were obtained, which all showed high levels after drought treatment. Notably, one R2R3-MYB transcription factor (Glyur000237s00014382.1), a critical regulator of flavonoid biosynthesis, achieved a significant upregulated expression as well. In the biosynthesis of glycyrrhizin, both gene and protein levels of bAS and CYP88D6 have been found with upregulated expression under drought conditions. Most of the differentially expressed genes (DEGs) and proteins (DEPs) showed similar expression patterns and positively related to metabolic profiles of flavonoid and saponin. We believe that suitable drought stress may contribute to the accumulation of bioactive constituents in licorice, and our research provides an insight into the genetic study and quality breeding in this plant." @default.
- W4387575958 created "2023-10-13" @default.
- W4387575958 creator A5019273238 @default.
- W4387575958 creator A5039128601 @default.
- W4387575958 creator A5041546288 @default.
- W4387575958 creator A5043689338 @default.
- W4387575958 creator A5045392886 @default.
- W4387575958 date "2023-10-12" @default.
- W4387575958 modified "2023-10-14" @default.
- W4387575958 title "Multi-Omics Elucidates Difference in Accumulation of Bioactive Constituents in Licorice (Glycyrrhiza uralensis) under Drought Stress" @default.
- W4387575958 cites W1608151639 @default.
- W4387575958 cites W1971953250 @default.
- W4387575958 cites W1980172418 @default.
- W4387575958 cites W2010224694 @default.
- W4387575958 cites W2025410007 @default.
- W4387575958 cites W2038940850 @default.
- W4387575958 cites W2055072891 @default.
- W4387575958 cites W2070429529 @default.
- W4387575958 cites W2084530483 @default.
- W4387575958 cites W2114384345 @default.
- W4387575958 cites W2311871742 @default.
- W4387575958 cites W2323397193 @default.
- W4387575958 cites W2345735224 @default.
- W4387575958 cites W2414012011 @default.
- W4387575958 cites W2534942962 @default.
- W4387575958 cites W2596059881 @default.
- W4387575958 cites W2801776293 @default.
- W4387575958 cites W2894753795 @default.
- W4387575958 cites W2901653977 @default.
- W4387575958 cites W2904296772 @default.
- W4387575958 cites W2904620942 @default.
- W4387575958 cites W2921653947 @default.
- W4387575958 cites W2938198177 @default.
- W4387575958 cites W2946006574 @default.
- W4387575958 cites W2949057465 @default.
- W4387575958 cites W2954104149 @default.
- W4387575958 cites W2972889883 @default.
- W4387575958 cites W2976115057 @default.
- W4387575958 cites W2979754275 @default.
- W4387575958 cites W2998111149 @default.
- W4387575958 cites W2999748704 @default.
- W4387575958 cites W3004121954 @default.
- W4387575958 cites W3036970257 @default.
- W4387575958 cites W3099497285 @default.
- W4387575958 cites W3113036654 @default.
- W4387575958 cites W3139343904 @default.
- W4387575958 cites W3174254987 @default.
- W4387575958 cites W3203501137 @default.
- W4387575958 cites W3204971966 @default.
- W4387575958 cites W3216174003 @default.
- W4387575958 cites W4220965417 @default.
- W4387575958 cites W4283575177 @default.
- W4387575958 cites W4284988229 @default.
- W4387575958 cites W4293207194 @default.
- W4387575958 cites W4303946626 @default.
- W4387575958 cites W4318592077 @default.
- W4387575958 cites W4319869025 @default.
- W4387575958 cites W4322574941 @default.
- W4387575958 cites W4361005253 @default.
- W4387575958 cites W4387454654 @default.
- W4387575958 doi "https://doi.org/10.3390/molecules28207042" @default.
- W4387575958 hasPublicationYear "2023" @default.
- W4387575958 type Work @default.
- W4387575958 citedByCount "0" @default.
- W4387575958 crossrefType "journal-article" @default.
- W4387575958 hasAuthorship W4387575958A5019273238 @default.
- W4387575958 hasAuthorship W4387575958A5039128601 @default.
- W4387575958 hasAuthorship W4387575958A5041546288 @default.
- W4387575958 hasAuthorship W4387575958A5043689338 @default.
- W4387575958 hasAuthorship W4387575958A5045392886 @default.
- W4387575958 hasBestOaLocation W43875759581 @default.
- W4387575958 hasConcept C104317684 @default.
- W4387575958 hasConcept C104397665 @default.
- W4387575958 hasConcept C135870905 @default.
- W4387575958 hasConcept C142724271 @default.
- W4387575958 hasConcept C150194340 @default.
- W4387575958 hasConcept C152724338 @default.
- W4387575958 hasConcept C162317418 @default.
- W4387575958 hasConcept C204787440 @default.
- W4387575958 hasConcept C21565614 @default.
- W4387575958 hasConcept C2778004101 @default.
- W4387575958 hasConcept C2778564307 @default.
- W4387575958 hasConcept C2779054382 @default.
- W4387575958 hasConcept C2779655422 @default.
- W4387575958 hasConcept C2780004758 @default.
- W4387575958 hasConcept C2780527577 @default.
- W4387575958 hasConcept C44937612 @default.
- W4387575958 hasConcept C553450214 @default.
- W4387575958 hasConcept C55493867 @default.
- W4387575958 hasConcept C60644358 @default.
- W4387575958 hasConcept C71924100 @default.
- W4387575958 hasConcept C86803240 @default.
- W4387575958 hasConceptScore W4387575958C104317684 @default.
- W4387575958 hasConceptScore W4387575958C104397665 @default.
- W4387575958 hasConceptScore W4387575958C135870905 @default.
- W4387575958 hasConceptScore W4387575958C142724271 @default.
- W4387575958 hasConceptScore W4387575958C150194340 @default.
- W4387575958 hasConceptScore W4387575958C152724338 @default.