Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387576422> ?p ?o ?g. }
- W4387576422 abstract "The mammalian zygote, formed after a sperm fertilizes an egg, undergoes several rounds of mitosis and morphogenesis to form the blastocyst. During the peri-implantation period, the blastocyst hatches out of the zona pellucida (ZP) and invades the receptive uterine endometrium. This process promotes maternal-fetal dialogue at the physiological and molecular level, thereby initiating the implantation process. Blastocyst hatching is a consequence of elevated osmotic pressure due to active Na+/K+ ion transporter in the blastocyst cavity, as well as proteases produced by trophectoderm (TE) that hydrolyze the ZP. This review summarizes the process underpinning blastocyst hatching, such as the hatching schedule, the location of TEs during initial hatching out of the ZP, the molecules involved in blastocyst hatching, and how these processes affect implantation events. Additionally, we focus on identifying crucial molecules that may influence the quality of implantation and predict the outcome of embryo implantation. Further understanding the mechanism of these molecules may help us to improve the efficiency of Assisted reproductive technology (ART) in livestock breeding. This review provides insight into embryonic development, specifically during the short-term process of blastocyst hatching and its effects on the following implantation." @default.
- W4387576422 created "2023-10-13" @default.
- W4387576422 creator A5004636265 @default.
- W4387576422 creator A5013490723 @default.
- W4387576422 creator A5026872651 @default.
- W4387576422 creator A5052159732 @default.
- W4387576422 creator A5066599847 @default.
- W4387576422 creator A5074338325 @default.
- W4387576422 creator A5076901413 @default.
- W4387576422 date "2023-10-01" @default.
- W4387576422 modified "2023-10-14" @default.
- W4387576422 title "Effect of blastocyst development on hatching and embryo implantation" @default.
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