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- W4387586622 abstract "Congenital adrenal hyperplasia (CAH) in its severe salt-wasting form is a challenge for pediatric endocrinologists in order to maintain water and sodium homeostasis, particularly in the neonatal period. The pathophysiology of this impaired sodium balance is still poorly investigated as well as its therapeutic management. This chapter will summarize mechanisms of sodium and water reabsorption, particularly the aldosterone-mineralocorticoid receptor signaling pathway, its expression and regulation in neonates, and the impact of a complete 21-hydroxylase deficiency." @default.
- W4387586622 created "2023-10-13" @default.
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- W4387586622 date "2023-01-01" @default.
- W4387586622 modified "2023-10-14" @default.
- W4387586622 title "Electrolyte Disturbance in Congenital Adrenal Hyperplasia due to 21-OH Deficiency" @default.
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- W4387586622 doi "https://doi.org/10.1007/978-3-031-27119-9_9" @default.
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