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- W4387588377 abstract "In recent years, more and more studies have shown that microRNA-29a (miRNA-29a) can be used as a potential biomarker for active tuberculosis, but the results of these studies are not consistent.To comprehensively evaluate the value of miRNA-29a in the diagnosis of active tuberculosis by meta-analysis.The databases of CNKI, WanFang, PubMed, The Cochrane Library, Web of Science and EMBASE were searched for relevant studies. Studies were screened strictly according to inclusion and exclusion criteria. QUADAS-2 scale was used to evaluate the quality of the included studies. Data were extracted and analyzed by Meta-DiSc 1.4 and Stata 16.0 software.13 articles were included, including a total of 1598 subjects, including 872 active tuberculosis patients and 726 controls. The combined sensitivity and specificity of miRNA-29a in the diagnosis of active tuberculosis were 78 % and 76 %, respectively, and the area under the overall summary receiver operating characteristic curve was 0.8564.miRNA-29a can be used as a biomarker for the diagnosis of active tuberculosis." @default.
- W4387588377 created "2023-10-13" @default.
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- W4387588377 date "2023-01-01" @default.
- W4387588377 modified "2023-10-16" @default.
- W4387588377 title "Diagnostic performance of microRNA-29a in active pulmonary tuberculosis: a systematic review and meta-analysis" @default.
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- W4387588377 doi "https://doi.org/10.1016/j.clinsp.2023.100290" @default.
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