FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387597497> ?p ?o ?g. }

• W4387597497 abstract "Background Postacute sequelae of COVID-19 (PASC) and HIV are both associated with reduced exercise capacity, but whether SARS-CoV-2 or PASC are associated with exercise capacity among people with HIV (PWH) is unknown. We hypothesized that PWH with PASC would have reduced exercise capacity from chronotropic incompetence. Methods and Results We conducted cross-sectional cardiopulmonary exercise testing within a COVID recovery cohort that included PWH with and without prior SARS-CoV-2 infection and people without HIV with prior SARS-CoV-2 infection (controls). We evaluated associations of HIV, SARS-CoV-2, and PASC with exercise capacity (peak oxygen consumption) and chronotropy (adjusted heart rate reserve). We included 83 participants (median age, 54 years; 35% women; 37 PWH): 23 out of 37 (62%) PWH and all 46 controls had prior SARS-CoV-2 infection, and 11 out of 23 (48%) PWH and 28 out of 46 (61%) without HIV had PASC. Peak oxygen consumption was reduced among PWH versus controls (80% predicted versus 99%, P=0.005), a difference of 5.5 mL/kg per minute (95% CI, 2.7-8.2; P<0.001). Chronotropic incompetence was more prevalent among PWH (38% versus 11%, P=0.002), with lower adjusted heart rate reserve (60% versus 83%, P<0.0001) versus controls. Among PWH, SARS-CoV-2 coinfection and PASC were not associated with exercise capacity. Chronotropic incompetence was more common among PWH with PASC: 7 out of 11 (64%) with PASC versus 7 out of 26 (27%) without PASC (P=0.04). Conclusions Exercise capacity and chronotropy are lower among PWH compared with individuals with SARS-CoV-2 infection without HIV. Among PWH, SARS-CoV-2 infection and PASC were not strongly associated with reduced exercise capacity. Chronotropic incompetence may be a common underrecognized mechanism of exercise intolerance among PWH, especially those with cardiopulmonary PASC." @default.
• W4387597497 created "2023-10-14" @default.
• W4387597497 creator A5002449091 @default.
• W4387597497 creator A5004544366 @default.
• W4387597497 creator A5004908163 @default.
• W4387597497 creator A5012913900 @default.
• W4387597497 creator A5020589345 @default.
• W4387597497 creator A5025067591 @default.
• W4387597497 creator A5025775968 @default.
• W4387597497 creator A5026951319 @default.
• W4387597497 creator A5031631673 @default.
• W4387597497 creator A5033146175 @default.
• W4387597497 creator A5042931433 @default.
• W4387597497 creator A5044517988 @default.
• W4387597497 creator A5045440876 @default.
• W4387597497 creator A5074125267 @default.
• W4387597497 creator A5082928749 @default.
• W4387597497 date "2023-10-13" @default.
• W4387597497 modified "2023-10-18" @default.
• W4387597497 title "Association of SARS‐CoV‐2 Infection and Cardiopulmonary Long COVID With Exercise Capacity and Chronotropic Incompetence Among People With HIV" @default.
• W4387597497 cites W1971474283 @default.
• W4387597497 cites W1972993182 @default.
• W4387597497 cites W1976102541 @default.
• W4387597497 cites W1981949840 @default.
• W4387597497 cites W1991401556 @default.
• W4387597497 cites W2002077045 @default.
• W4387597497 cites W2009587500 @default.
• W4387597497 cites W2021361540 @default.
• W4387597497 cites W2024453052 @default.
• W4387597497 cites W2034784218 @default.
• W4387597497 cites W2069884759 @default.
• W4387597497 cites W2074602210 @default.
• W4387597497 cites W2081586596 @default.
• W4387597497 cites W2090875077 @default.
• W4387597497 cites W2101791328 @default.
• W4387597497 cites W2108605012 @default.
• W4387597497 cites W2109984600 @default.
• W4387597497 cites W2132084610 @default.
• W4387597497 cites W2136116352 @default.
• W4387597497 cites W2139219244 @default.
• W4387597497 cites W2141376917 @default.
• W4387597497 cites W2163066404 @default.
• W4387597497 cites W21944932 @default.
• W4387597497 cites W2217600751 @default.
• W4387597497 cites W2472837637 @default.
• W4387597497 cites W2528003753 @default.
• W4387597497 cites W2563198170 @default.
• W4387597497 cites W2604509865 @default.
• W4387597497 cites W2613330526 @default.
• W4387597497 cites W2770535841 @default.
• W4387597497 cites W2798244438 @default.
• W4387597497 cites W2888710315 @default.
• W4387597497 cites W2941357110 @default.
• W4387597497 cites W2972877036 @default.
• W4387597497 cites W2984846742 @default.
• W4387597497 cites W2995563102 @default.
• W4387597497 cites W3011986409 @default.
• W4387597497 cites W3047147464 @default.
• W4387597497 cites W3092296929 @default.
• W4387597497 cites W3112095389 @default.
• W4387597497 cites W3158627808 @default.
• W4387597497 cites W3163897922 @default.
• W4387597497 cites W3168262242 @default.
• W4387597497 cites W4200212226 @default.
• W4387597497 cites W4210975502 @default.
• W4387597497 cites W4225619408 @default.
• W4387597497 cites W4281401657 @default.
• W4387597497 cites W4286563176 @default.
• W4387597497 cites W4304695132 @default.
• W4387597497 cites W4310494031 @default.
• W4387597497 cites W4323255633 @default.
• W4387597497 cites W4327918526 @default.
• W4387597497 cites W4376133067 @default.
• W4387597497 doi "https://doi.org/10.1161/jaha.123.030896" @default.
• W4387597497 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37830367" @default.
• W4387597497 hasPublicationYear "2023" @default.
• W4387597497 type Work @default.
• W4387597497 citedByCount "0" @default.
• W4387597497 crossrefType "journal-article" @default.
• W4387597497 hasAuthorship W4387597497A5002449091 @default.
• W4387597497 hasAuthorship W4387597497A5004544366 @default.
• W4387597497 hasAuthorship W4387597497A5004908163 @default.
• W4387597497 hasAuthorship W4387597497A5012913900 @default.
• W4387597497 hasAuthorship W4387597497A5020589345 @default.
• W4387597497 hasAuthorship W4387597497A5025067591 @default.
• W4387597497 hasAuthorship W4387597497A5025775968 @default.
• W4387597497 hasAuthorship W4387597497A5026951319 @default.
• W4387597497 hasAuthorship W4387597497A5031631673 @default.
• W4387597497 hasAuthorship W4387597497A5033146175 @default.
• W4387597497 hasAuthorship W4387597497A5042931433 @default.
• W4387597497 hasAuthorship W4387597497A5044517988 @default.
• W4387597497 hasAuthorship W4387597497A5045440876 @default.
• W4387597497 hasAuthorship W4387597497A5074125267 @default.
• W4387597497 hasAuthorship W4387597497A5082928749 @default.
• W4387597497 hasBestOaLocation W43875974971 @default.
• W4387597497 hasConcept C126322002 @default.
• W4387597497 hasConcept C151956035 @default.
• W4387597497 hasConcept C158328960 @default.
• W4387597497 hasConcept C164705383 @default.
• W4387597497 hasConcept C1862650 @default.

• next