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- W4387598571 abstract "Atorvastatin, a lipid-lowering drug that is widely used in the treatment of cardiovascular diseases, has significant clinical significance. This article focuses on the synthetic procedures of atorvastatin, including Paal-Knorr synthesis and several new synthetic strategies. It also outlines chemical and chemo-enzymatic methods for synthesizing optically active side chain of atorvastatin. In addition, a comprehensive overview of the analytical monitoring techniques for atorvastatin and its metabolites and impurities is reported, alongside a discussion of their strengths and limitations." @default.
- W4387598571 created "2023-10-14" @default.
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- W4387598571 date "2023-10-11" @default.
- W4387598571 modified "2023-10-14" @default.
- W4387598571 title "Recent Advances in the Synthesis and Analysis of Atorvastatin and its Intermediates" @default.
- W4387598571 doi "https://doi.org/10.2174/0109298673263728231004053704" @default.
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