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- W4387599775 abstract "Aim: This study evaluated the antifungal efficacy of gentian violet (GV) in an experimental vulvovaginal candidiasis (VVC) model. Materials & methods:In vitro susceptibility and cytotoxicity assays were performed to validate the antifungal potential and safety of GV. The antifungal efficacy was then evaluated in vivo through comparative analysis of the fungal burden following treatment with GV or nystatin, as well as assessment of the vaginal tissue by histology and electron microscopy. Results: GV demonstrated a safe antifungal profile against C. albicans, with a significant decrease in fungal burden and an improvement in the inflammatory process evaluated histologically. Conclusion: The results of this study motivate further assessment of GV as a promising alternative for VVC therapy." @default.
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- W4387599775 date "2023-10-13" @default.
- W4387599775 modified "2023-10-14" @default.
- W4387599775 title "Successful treatment of experimental murine vulvovaginal candidiasis with gentian violet" @default.
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- W4387599775 doi "https://doi.org/10.2217/fmb-2023-0021" @default.
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