Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387642717> ?p ?o ?g. }
- W4387642717 endingPage "8453" @default.
- W4387642717 startingPage "8453" @default.
- W4387642717 abstract "Measurement of the intracellular pH is particularly crucial for the detection of numerous diseases, such as carcinomas, that are characterised by a low intracellular pH. Therefore, pH-responsive nanosensors have been developed by many researchers due to their ability to non-invasively detect minor changes in the pH of many biological systems without causing significant biological damage. However, the existing pH-sensitive nanosensors, such as the polyacrylamide, silica, and quantum dots-based nanosensors, require large quantities of organic solvents that could cause detrimental damage to the ecosystem. As a result, this research is aimed at developing a new generation of pH-responsive nanosensors comprising alginate natural polymers and pH-sensitive fluorophores using an organic, solvent-free, and ecologically friendly method. Herein, we successfully synthesised different models of pH-responsive alginate nanoparticles by varying the method of fluorophore conjugation. The synthesised pH nanosensors demonstrated a low MHD with a relatively acceptable PDI when using the lowest concentration of the cross-linker Ca+2 (1.25 mM). All the pH nanosensors showed negative zeta potential values, attributed to the free carboxylate groups surrounding the nanoparticles’ surfaces, which support the colloidal stability of the nanosensors. The synthesised models of pH nanosensors displayed a high pH-responsiveness with various correlations between the pH measurements and the nanosensors’ fluorescence signal. In summation, pH-responsive alginate nanosensors produced using organic, solvent-free, green technology could be harnessed as potential diagnostics for the intracellular and extracellular pH measurements of various biological systems." @default.
- W4387642717 created "2023-10-15" @default.
- W4387642717 creator A5033296275 @default.
- W4387642717 creator A5038489458 @default.
- W4387642717 creator A5049614029 @default.
- W4387642717 creator A5078262052 @default.
- W4387642717 creator A5088717343 @default.
- W4387642717 creator A5089979499 @default.
- W4387642717 creator A5093064454 @default.
- W4387642717 date "2023-10-13" @default.
- W4387642717 modified "2023-10-15" @default.
- W4387642717 title "Development of a Novel, Ecologically Friendly Generation of pH-Responsive Alginate Nanosensors: Synthesis, Calibration, and Characterisation" @default.
- W4387642717 cites W1562749775 @default.
- W4387642717 cites W1967103797 @default.
- W4387642717 cites W1970718457 @default.
- W4387642717 cites W1974898755 @default.
- W4387642717 cites W1981058171 @default.
- W4387642717 cites W1991585202 @default.
- W4387642717 cites W1998972039 @default.
- W4387642717 cites W2006685379 @default.
- W4387642717 cites W2017046772 @default.
- W4387642717 cites W2040809317 @default.
- W4387642717 cites W2063343818 @default.
- W4387642717 cites W2079276252 @default.
- W4387642717 cites W2082454728 @default.
- W4387642717 cites W2083893611 @default.
- W4387642717 cites W2093073082 @default.
- W4387642717 cites W2097137275 @default.
- W4387642717 cites W2148087335 @default.
- W4387642717 cites W2153572376 @default.
- W4387642717 cites W2157319518 @default.
- W4387642717 cites W2174398172 @default.
- W4387642717 cites W2184975991 @default.
- W4387642717 cites W2285026259 @default.
- W4387642717 cites W2292437912 @default.
- W4387642717 cites W2418601768 @default.
- W4387642717 cites W2516880872 @default.
- W4387642717 cites W2530198880 @default.
- W4387642717 cites W2606683336 @default.
- W4387642717 cites W2620608457 @default.
- W4387642717 cites W2793521545 @default.
- W4387642717 cites W2805151108 @default.
- W4387642717 cites W2889233911 @default.
- W4387642717 cites W2896778602 @default.
- W4387642717 cites W2915063419 @default.
- W4387642717 cites W2933021827 @default.
- W4387642717 cites W2995752223 @default.
- W4387642717 cites W3046311274 @default.
- W4387642717 cites W3048666653 @default.
- W4387642717 cites W3120768973 @default.
- W4387642717 cites W3172550438 @default.
- W4387642717 cites W4254166813 @default.
- W4387642717 cites W4296804049 @default.
- W4387642717 cites W4313389054 @default.
- W4387642717 cites W4368372811 @default.
- W4387642717 cites W572781277 @default.
- W4387642717 doi "https://doi.org/10.3390/s23208453" @default.
- W4387642717 hasPublicationYear "2023" @default.
- W4387642717 type Work @default.
- W4387642717 citedByCount "0" @default.
- W4387642717 crossrefType "journal-article" @default.
- W4387642717 hasAuthorship W4387642717A5033296275 @default.
- W4387642717 hasAuthorship W4387642717A5038489458 @default.
- W4387642717 hasAuthorship W4387642717A5049614029 @default.
- W4387642717 hasAuthorship W4387642717A5078262052 @default.
- W4387642717 hasAuthorship W4387642717A5088717343 @default.
- W4387642717 hasAuthorship W4387642717A5089979499 @default.
- W4387642717 hasAuthorship W4387642717A5093064454 @default.
- W4387642717 hasBestOaLocation W43876427171 @default.
- W4387642717 hasConcept C121332964 @default.
- W4387642717 hasConcept C155672457 @default.
- W4387642717 hasConcept C171250308 @default.
- W4387642717 hasConcept C185592680 @default.
- W4387642717 hasConcept C192562407 @default.
- W4387642717 hasConcept C41858301 @default.
- W4387642717 hasConcept C62520636 @default.
- W4387642717 hasConcept C91881484 @default.
- W4387642717 hasConceptScore W4387642717C121332964 @default.
- W4387642717 hasConceptScore W4387642717C155672457 @default.
- W4387642717 hasConceptScore W4387642717C171250308 @default.
- W4387642717 hasConceptScore W4387642717C185592680 @default.
- W4387642717 hasConceptScore W4387642717C192562407 @default.
- W4387642717 hasConceptScore W4387642717C41858301 @default.
- W4387642717 hasConceptScore W4387642717C62520636 @default.
- W4387642717 hasConceptScore W4387642717C91881484 @default.
- W4387642717 hasFunder F4320323502 @default.
- W4387642717 hasIssue "20" @default.
- W4387642717 hasLocation W43876427171 @default.
- W4387642717 hasOpenAccess W4387642717 @default.
- W4387642717 hasPrimaryLocation W43876427171 @default.
- W4387642717 hasRelatedWork W2089770167 @default.
- W4387642717 hasRelatedWork W2124508569 @default.
- W4387642717 hasRelatedWork W2152223091 @default.
- W4387642717 hasRelatedWork W2188796877 @default.
- W4387642717 hasRelatedWork W2742447846 @default.
- W4387642717 hasRelatedWork W2890344412 @default.
- W4387642717 hasRelatedWork W2899084033 @default.
- W4387642717 hasRelatedWork W3043329414 @default.