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- W4387643460 endingPage "127410" @default.
- W4387643460 startingPage "127410" @default.
- W4387643460 abstract "Biomaterials play a fundamental role in tissue engineering by providing biochemical and physical cues that influence cellular fate and matrix development. Decellularized extracellular matrix (dECM) as a biomaterial is distinguished by its abundant composition of matrix proteins, such as collagen, elastin, fibronectin, and laminin, as well as glycosaminoglycans and proteoglycans. However, the mechanical properties of only dECM-based constructs may not always meet tissue-specific requirements. Recent advancements address this challenge by utilizing hybrid biomaterials that harness the strengths of silk fibroin (SF), which contributes the necessary mechanical properties, while dECM provides essential cellular cues for in vitro studies and tissue regeneration. This review discusses emerging trends in developing such biopolymer blends, aiming to synergistically combine the advantages of SF and dECM through optimal concentrations and desired cross-linking density. We focus on different fabrication techniques and cross-linking methods that have been utilized to fabricate various tissue-engineered hybrid constructs. Furthermore, we survey recent applications of such biomaterials for the regeneration of various tissues, including bone, cartilage, trachea, bladder, vascular graft, heart, skin, liver, and other soft tissues. Finally, the trajectory and prospects of the constructs derived from this blend in the tissue engineering field have been summarized, highlighting their potential for clinical translation." @default.
- W4387643460 created "2023-10-15" @default.
- W4387643460 creator A5020707741 @default.
- W4387643460 creator A5088113593 @default.
- W4387643460 date "2023-10-01" @default.
- W4387643460 modified "2023-10-18" @default.
- W4387643460 title "Decellularized extracellular matrix and silk fibroin-based hybrid biomaterials: A comprehensive review on fabrication techniques and tissue-specific applications" @default.
- W4387643460 cites W1953179980 @default.
- W4387643460 cites W1964356620 @default.
- W4387643460 cites W1972067639 @default.
- W4387643460 cites W1973623380 @default.
- W4387643460 cites W1975730998 @default.
- W4387643460 cites W1976111379 @default.
- W4387643460 cites W1979462929 @default.
- W4387643460 cites W1983707837 @default.
- W4387643460 cites W1988510537 @default.
- W4387643460 cites W1999039522 @default.
- W4387643460 cites W2001380203 @default.
- W4387643460 cites W2003563357 @default.
- W4387643460 cites W2020617826 @default.
- W4387643460 cites W2022106720 @default.
- W4387643460 cites W2026799007 @default.
- W4387643460 cites W2026898869 @default.
- W4387643460 cites W2028509138 @default.
- W4387643460 cites W2031095949 @default.
- W4387643460 cites W2031344083 @default.
- W4387643460 cites W2034855615 @default.
- W4387643460 cites W2040264885 @default.
- W4387643460 cites W2050875646 @default.
- W4387643460 cites W2052116137 @default.
- W4387643460 cites W2059486645 @default.
- W4387643460 cites W2063087782 @default.
- W4387643460 cites W2068305554 @default.
- W4387643460 cites W2070938235 @default.
- W4387643460 cites W2074554495 @default.
- W4387643460 cites W2084515183 @default.
- W4387643460 cites W2094650509 @default.
- W4387643460 cites W2110032671 @default.
- W4387643460 cites W2110505789 @default.
- W4387643460 cites W2127461057 @default.
- W4387643460 cites W2133476128 @default.
- W4387643460 cites W2133683725 @default.
- W4387643460 cites W2134594378 @default.
- W4387643460 cites W2136585808 @default.
- W4387643460 cites W2141284915 @default.
- W4387643460 cites W2147426059 @default.
- W4387643460 cites W2150479935 @default.
- W4387643460 cites W2171925711 @default.
- W4387643460 cites W2191751320 @default.
- W4387643460 cites W2194732621 @default.
- W4387643460 cites W2265139335 @default.
- W4387643460 cites W2340116897 @default.
- W4387643460 cites W2484861867 @default.
- W4387643460 cites W2497042995 @default.
- W4387643460 cites W2503067859 @default.
- W4387643460 cites W2504826727 @default.
- W4387643460 cites W2561319457 @default.
- W4387643460 cites W2575229100 @default.
- W4387643460 cites W2589394758 @default.
- W4387643460 cites W2589606226 @default.
- W4387643460 cites W2603172797 @default.
- W4387643460 cites W2606843135 @default.
- W4387643460 cites W2739557621 @default.
- W4387643460 cites W2754535854 @default.
- W4387643460 cites W2756378009 @default.
- W4387643460 cites W2756437510 @default.
- W4387643460 cites W2765826316 @default.
- W4387643460 cites W2766770514 @default.
- W4387643460 cites W2767280943 @default.
- W4387643460 cites W2768858170 @default.
- W4387643460 cites W2769981674 @default.
- W4387643460 cites W2772342946 @default.
- W4387643460 cites W2774372483 @default.
- W4387643460 cites W2777795176 @default.
- W4387643460 cites W2780132385 @default.
- W4387643460 cites W2789567970 @default.
- W4387643460 cites W2789649370 @default.
- W4387643460 cites W2797163462 @default.
- W4387643460 cites W2799345614 @default.
- W4387643460 cites W2800442720 @default.
- W4387643460 cites W2801476438 @default.
- W4387643460 cites W2802504186 @default.
- W4387643460 cites W2804910207 @default.
- W4387643460 cites W2884071049 @default.
- W4387643460 cites W2887455964 @default.
- W4387643460 cites W2893267824 @default.
- W4387643460 cites W2896145416 @default.
- W4387643460 cites W2896446481 @default.
- W4387643460 cites W2898125178 @default.
- W4387643460 cites W2899366145 @default.
- W4387643460 cites W2900709212 @default.
- W4387643460 cites W2901631637 @default.
- W4387643460 cites W2904444744 @default.
- W4387643460 cites W2905964845 @default.
- W4387643460 cites W2908475303 @default.
- W4387643460 cites W2908889018 @default.
- W4387643460 cites W2911944249 @default.
- W4387643460 cites W2914095071 @default.