Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387644443> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W4387644443 abstract "Objective
 Skeletal muscle loss is an indicator of cachexia and a strong prognostic factor for some types of cancer. After strict standardization, we aim to evaluate both the predictive and prognostic value of low muscle mass (LMM) in common cancer types for first-line chemotherapy.
 Material and Methods
 This retrospective single-center study was conducted in a regional hospital between 2015-2020. Patients diagnosed with distant metastatic cancer were screened and included in the study if patients had abdominal computed tomography 45 days prior to first-line chemotherapy. The relationship between LMM and progression free survival (PFS), overall survival (OS), and objective response rate (ORR) were evaluated.
 Results
 Initially, 289 patients with metastatic cancer were included, median duration of follow-up was 17 months, mean age was 61.09±13.03 years (range 25 to 95), and 45.9% of patients were female. In total, 50.5% of patients had LMM which was adjusted for gender. LMM was associated with worse PFS and OS in univariate analysis (HR:1.583;1.216-2.059; p=0.001 for PFS and HR:1.598;1.216-2.100; p=0.001 for OS) and this positive association was maintained after adjusted for diagnosis and age. Better ORRs were obtained in respiratory and gastrointestinal tract cancers, breast, prostate and gynecological cancer in non-LMM groups.
 Conclusions
 LMM has not only prognostic value but also predictive value for many types of cancer. Therefore, assessment of muscle loss should be incorporated as part of the initial routine clinical evaluation." @default.
- W4387644443 created "2023-10-15" @default.
- W4387644443 creator A5027004394 @default.
- W4387644443 creator A5034016441 @default.
- W4387644443 creator A5039600560 @default.
- W4387644443 creator A5067619596 @default.
- W4387644443 creator A5087227279 @default.
- W4387644443 date "2023-09-06" @default.
- W4387644443 modified "2023-10-15" @default.
- W4387644443 title "Uzak metastazlı kanser hastalarında iskelet kası kütlesinin prediktif ve prognostik değeri" @default.
- W4387644443 cites W1647885568 @default.
- W4387644443 cites W1684577264 @default.
- W4387644443 cites W1880408623 @default.
- W4387644443 cites W2063334442 @default.
- W4387644443 cites W2097022747 @default.
- W4387644443 cites W2118558111 @default.
- W4387644443 cites W2118598881 @default.
- W4387644443 cites W2129921842 @default.
- W4387644443 cites W2505846117 @default.
- W4387644443 cites W2540033076 @default.
- W4387644443 cites W2784999756 @default.
- W4387644443 cites W2802320119 @default.
- W4387644443 cites W3011896336 @default.
- W4387644443 cites W3016294104 @default.
- W4387644443 cites W3118321014 @default.
- W4387644443 cites W3127057265 @default.
- W4387644443 doi "https://doi.org/10.30565/medalanya.1167930" @default.
- W4387644443 hasPublicationYear "2023" @default.
- W4387644443 type Work @default.
- W4387644443 citedByCount "0" @default.
- W4387644443 crossrefType "journal-article" @default.
- W4387644443 hasAuthorship W4387644443A5027004394 @default.
- W4387644443 hasAuthorship W4387644443A5034016441 @default.
- W4387644443 hasAuthorship W4387644443A5039600560 @default.
- W4387644443 hasAuthorship W4387644443A5067619596 @default.
- W4387644443 hasAuthorship W4387644443A5087227279 @default.
- W4387644443 hasBestOaLocation W43876444431 @default.
- W4387644443 hasConcept C121608353 @default.
- W4387644443 hasConcept C126322002 @default.
- W4387644443 hasConcept C143998085 @default.
- W4387644443 hasConcept C144301174 @default.
- W4387644443 hasConcept C2776694085 @default.
- W4387644443 hasConcept C2780192828 @default.
- W4387644443 hasConcept C29456083 @default.
- W4387644443 hasConcept C38180746 @default.
- W4387644443 hasConcept C530470458 @default.
- W4387644443 hasConcept C71924100 @default.
- W4387644443 hasConceptScore W4387644443C121608353 @default.
- W4387644443 hasConceptScore W4387644443C126322002 @default.
- W4387644443 hasConceptScore W4387644443C143998085 @default.
- W4387644443 hasConceptScore W4387644443C144301174 @default.
- W4387644443 hasConceptScore W4387644443C2776694085 @default.
- W4387644443 hasConceptScore W4387644443C2780192828 @default.
- W4387644443 hasConceptScore W4387644443C29456083 @default.
- W4387644443 hasConceptScore W4387644443C38180746 @default.
- W4387644443 hasConceptScore W4387644443C530470458 @default.
- W4387644443 hasConceptScore W4387644443C71924100 @default.
- W4387644443 hasLocation W43876444431 @default.
- W4387644443 hasOpenAccess W4387644443 @default.
- W4387644443 hasPrimaryLocation W43876444431 @default.
- W4387644443 hasRelatedWork W151774199 @default.
- W4387644443 hasRelatedWork W2071753433 @default.
- W4387644443 hasRelatedWork W209797606 @default.
- W4387644443 hasRelatedWork W2345040638 @default.
- W4387644443 hasRelatedWork W2384122898 @default.
- W4387644443 hasRelatedWork W2557359331 @default.
- W4387644443 hasRelatedWork W2892677547 @default.
- W4387644443 hasRelatedWork W3171449477 @default.
- W4387644443 hasRelatedWork W4281885123 @default.
- W4387644443 hasRelatedWork W299695548 @default.
- W4387644443 isParatext "false" @default.
- W4387644443 isRetracted "false" @default.
- W4387644443 workType "article" @default.