Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387651929> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W4387651929 abstract "Pigs are important animals for meat production but can carry several zoonotic diseases, including Japanese encephalitis virus, Nipah virus, and influenza viruses. Several Orthomyxoviridae and Coronavirinae respiratory viruses require cleavage of envelope proteins to acquire viral infectivity and consequently need a host protease or the addition of exogenous trypsin for efficient propagation. Host TMPRSS2 is a key protease responsible for viral cleavage. Stable expression of human TMPRSS2 in African green monkey-derived Vero cells can enhance the porcine epidemic diarrhea virus. However, considering the narrow host tropism of viruses, a porcine cell line expressing pig TMPRSS2 could be optimal for replicating pig-derived viruses. Herein, we generated and evaluated a pig-derived PK-15 cell line stably expressing pig TMPRSS2. This cell line markedly and specifically enhanced the growth of influenza viruses. Therefore, PK-15 cells expressing pig TMPRSS2 could be a valuable and promising tool for virus isolation, vaccine production, and virological studies." @default.
- W4387651929 created "2023-10-16" @default.
- W4387651929 creator A5010617996 @default.
- W4387651929 creator A5015659608 @default.
- W4387651929 creator A5019625529 @default.
- W4387651929 creator A5025022383 @default.
- W4387651929 creator A5027827712 @default.
- W4387651929 creator A5089458500 @default.
- W4387651929 creator A5090017776 @default.
- W4387651929 date "2023-10-15" @default.
- W4387651929 modified "2023-10-16" @default.
- W4387651929 title "Generation of a porcine cell line stably expressing pig TMPRSS2 for efficient isolation of viruses from pigs with respiratory diseases" @default.
- W4387651929 doi "https://doi.org/10.1101/2023.10.14.562371" @default.
- W4387651929 hasPublicationYear "2023" @default.
- W4387651929 type Work @default.
- W4387651929 citedByCount "0" @default.
- W4387651929 crossrefType "posted-content" @default.
- W4387651929 hasAuthorship W4387651929A5010617996 @default.
- W4387651929 hasAuthorship W4387651929A5015659608 @default.
- W4387651929 hasAuthorship W4387651929A5019625529 @default.
- W4387651929 hasAuthorship W4387651929A5025022383 @default.
- W4387651929 hasAuthorship W4387651929A5027827712 @default.
- W4387651929 hasAuthorship W4387651929A5089458500 @default.
- W4387651929 hasAuthorship W4387651929A5090017776 @default.
- W4387651929 hasBestOaLocation W43876519291 @default.
- W4387651929 hasConcept C106358424 @default.
- W4387651929 hasConcept C142724271 @default.
- W4387651929 hasConcept C159047783 @default.
- W4387651929 hasConcept C2522874641 @default.
- W4387651929 hasConcept C2775862345 @default.
- W4387651929 hasConcept C2777546802 @default.
- W4387651929 hasConcept C2778042024 @default.
- W4387651929 hasConcept C2779134260 @default.
- W4387651929 hasConcept C3008058167 @default.
- W4387651929 hasConcept C33602714 @default.
- W4387651929 hasConcept C35693153 @default.
- W4387651929 hasConcept C524204448 @default.
- W4387651929 hasConcept C54355233 @default.
- W4387651929 hasConcept C71924100 @default.
- W4387651929 hasConcept C81885089 @default.
- W4387651929 hasConcept C86803240 @default.
- W4387651929 hasConcept C89138240 @default.
- W4387651929 hasConcept C89423630 @default.
- W4387651929 hasConceptScore W4387651929C106358424 @default.
- W4387651929 hasConceptScore W4387651929C142724271 @default.
- W4387651929 hasConceptScore W4387651929C159047783 @default.
- W4387651929 hasConceptScore W4387651929C2522874641 @default.
- W4387651929 hasConceptScore W4387651929C2775862345 @default.
- W4387651929 hasConceptScore W4387651929C2777546802 @default.
- W4387651929 hasConceptScore W4387651929C2778042024 @default.
- W4387651929 hasConceptScore W4387651929C2779134260 @default.
- W4387651929 hasConceptScore W4387651929C3008058167 @default.
- W4387651929 hasConceptScore W4387651929C33602714 @default.
- W4387651929 hasConceptScore W4387651929C35693153 @default.
- W4387651929 hasConceptScore W4387651929C524204448 @default.
- W4387651929 hasConceptScore W4387651929C54355233 @default.
- W4387651929 hasConceptScore W4387651929C71924100 @default.
- W4387651929 hasConceptScore W4387651929C81885089 @default.
- W4387651929 hasConceptScore W4387651929C86803240 @default.
- W4387651929 hasConceptScore W4387651929C89138240 @default.
- W4387651929 hasConceptScore W4387651929C89423630 @default.
- W4387651929 hasLocation W43876519291 @default.
- W4387651929 hasOpenAccess W4387651929 @default.
- W4387651929 hasPrimaryLocation W43876519291 @default.
- W4387651929 hasRelatedWork W1502770178 @default.
- W4387651929 hasRelatedWork W1927653981 @default.
- W4387651929 hasRelatedWork W2362809315 @default.
- W4387651929 hasRelatedWork W2370504100 @default.
- W4387651929 hasRelatedWork W2371455924 @default.
- W4387651929 hasRelatedWork W2884776651 @default.
- W4387651929 hasRelatedWork W3087565161 @default.
- W4387651929 hasRelatedWork W3187476519 @default.
- W4387651929 hasRelatedWork W4210827144 @default.
- W4387651929 hasRelatedWork W4308875729 @default.
- W4387651929 isParatext "false" @default.
- W4387651929 isRetracted "false" @default.
- W4387651929 workType "article" @default.