Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387654447> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W4387654447 abstract "Background Time to treatment has been identified as a quality metric, with longer time to treatment associated with poorer outcomes. Genetic evaluation is an integral part of treatment counseling for patients with breast cancer. With expanding indications for genetic testing and consideration of expansion of genetic testing to all patients with a personal history of breast cancer, this study aims to evaluate the effect of genetic evaluation on the time interval from initial surgical visit to surgery. Methods A retrospective review of patients undergoing upfront surgery for stage 0–3 breast cancer from June 2022 to December 2022. Patient demographics, treatment characteristics, National Comprehensive Cancer Network criteria for genetic testing, and results were obtained. Results The study included 492 patients (489 females). Eighty-one (16.2%) were ≤50 years of age at diagnosis. In total, 281 patients (57.1%) met National Comprehensive Cancer Network criteria for genetic testing and 199 consulted with a genetic counselor (72.4%). Seventy-six patients (27.6%) not meeting National Comprehensive Cancer Network criteria pursued genetic counseling. In total, 218 patients (79.3%) referred for genetic counseling completed testing. Mean turnaround time to genetic testing result was 11 days (range, 6-66 days). Twenty-six patients (11.9%) had a pathogenic or likely pathogenic variant. Twenty-four of these patients met National Comprehensive Cancer Network testing criteria (92.3%) and 2 did not (7.7%). The time to treatment for patients undergoing genetic testing was 33 vs 34 days in those without testing (P = .45). Three patients (11.5%) with pathogenic or likely pathogenic variants altered their initial surgical plan due to their genetic testing results. Seven patients with pathogenic or likely pathogenic variant results returning postoperatively did not undergo additional surgery. Conclusion Hereditary breast cancer evaluation and genetic testing did not appear to delay time to treatment for patients with breast cancer in our study cohort." @default.
- W4387654447 created "2023-10-16" @default.
- W4387654447 creator A5014570917 @default.
- W4387654447 creator A5039784998 @default.
- W4387654447 creator A5040363564 @default.
- W4387654447 creator A5072371169 @default.
- W4387654447 creator A5092628345 @default.
- W4387654447 date "2023-10-01" @default.
- W4387654447 modified "2023-10-16" @default.
- W4387654447 title "Perioperative genetic testing and time to surgery in patients with breast cancer" @default.
- W4387654447 cites W1548773796 @default.
- W4387654447 cites W1952716868 @default.
- W4387654447 cites W1967690541 @default.
- W4387654447 cites W2024087900 @default.
- W4387654447 cites W2072567689 @default.
- W4387654447 cites W2142361813 @default.
- W4387654447 cites W2189708919 @default.
- W4387654447 cites W2313492784 @default.
- W4387654447 cites W2768922916 @default.
- W4387654447 cites W2783859624 @default.
- W4387654447 cites W2789183347 @default.
- W4387654447 cites W2794800920 @default.
- W4387654447 cites W2802287528 @default.
- W4387654447 cites W2810840855 @default.
- W4387654447 cites W2884503172 @default.
- W4387654447 cites W3015141169 @default.
- W4387654447 cites W3084669105 @default.
- W4387654447 cites W3124119591 @default.
- W4387654447 cites W3164066684 @default.
- W4387654447 cites W3166075610 @default.
- W4387654447 cites W3208085270 @default.
- W4387654447 cites W4206953151 @default.
- W4387654447 cites W4282580024 @default.
- W4387654447 cites W4310954081 @default.
- W4387654447 cites W4313892922 @default.
- W4387654447 cites W4315754639 @default.
- W4387654447 doi "https://doi.org/10.1016/j.surg.2023.08.043" @default.
- W4387654447 hasPublicationYear "2023" @default.
- W4387654447 type Work @default.
- W4387654447 citedByCount "0" @default.
- W4387654447 crossrefType "journal-article" @default.
- W4387654447 hasAuthorship W4387654447A5014570917 @default.
- W4387654447 hasAuthorship W4387654447A5039784998 @default.
- W4387654447 hasAuthorship W4387654447A5040363564 @default.
- W4387654447 hasAuthorship W4387654447A5072371169 @default.
- W4387654447 hasAuthorship W4387654447A5092628345 @default.
- W4387654447 hasConcept C121608353 @default.
- W4387654447 hasConcept C126322002 @default.
- W4387654447 hasConcept C141071460 @default.
- W4387654447 hasConcept C2780673598 @default.
- W4387654447 hasConcept C31174226 @default.
- W4387654447 hasConcept C530470458 @default.
- W4387654447 hasConcept C54355233 @default.
- W4387654447 hasConcept C71924100 @default.
- W4387654447 hasConcept C80227256 @default.
- W4387654447 hasConcept C86803240 @default.
- W4387654447 hasConceptScore W4387654447C121608353 @default.
- W4387654447 hasConceptScore W4387654447C126322002 @default.
- W4387654447 hasConceptScore W4387654447C141071460 @default.
- W4387654447 hasConceptScore W4387654447C2780673598 @default.
- W4387654447 hasConceptScore W4387654447C31174226 @default.
- W4387654447 hasConceptScore W4387654447C530470458 @default.
- W4387654447 hasConceptScore W4387654447C54355233 @default.
- W4387654447 hasConceptScore W4387654447C71924100 @default.
- W4387654447 hasConceptScore W4387654447C80227256 @default.
- W4387654447 hasConceptScore W4387654447C86803240 @default.
- W4387654447 hasLocation W43876544471 @default.
- W4387654447 hasOpenAccess W4387654447 @default.
- W4387654447 hasPrimaryLocation W43876544471 @default.
- W4387654447 hasRelatedWork W2006420298 @default.
- W4387654447 hasRelatedWork W2059304053 @default.
- W4387654447 hasRelatedWork W2134629356 @default.
- W4387654447 hasRelatedWork W2142174838 @default.
- W4387654447 hasRelatedWork W2538130930 @default.
- W4387654447 hasRelatedWork W2792273385 @default.
- W4387654447 hasRelatedWork W4210704068 @default.
- W4387654447 hasRelatedWork W4313489189 @default.
- W4387654447 hasRelatedWork W4323293767 @default.
- W4387654447 hasRelatedWork W4376872152 @default.
- W4387654447 isParatext "false" @default.
- W4387654447 isRetracted "false" @default.
- W4387654447 workType "article" @default.