Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387661917> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W4387661917 endingPage "934" @default.
- W4387661917 startingPage "926" @default.
- W4387661917 abstract "To systematically evaluate the effect of testosterone replacement therapy (TRT) on metabolic indexes in patients with hypogonadism.We searched the databases of CNKI, CBM, Wanfang Data, VIP, PubMed, Medline, Embase and Cochrane Library from the establishment to May 2021 for clinical randomized controlled trials (RCT) on the improvement of metabolic indexes of the patients with hypogonadism treated by TRT. According to the inclusion and excretion criteria, we screened the literature, extracted the data and evaluated the quality of the included RCTs, followed by statistical analysis with the STATA15.1 software.Totally 19 RCTs with 1 553 cases were included. Compared with placebo, TRT effectively reduced the levels of fasting plasma glucose (FPG) and fasting insulin (FINS), improved Homeostatic Model Assessment-insulin resistance (HOMA-IR), decreased total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C), increased the body mass index (BMI), lowered the waist circumference (WC), but elevated the systolic blood pressure (SBP) and diastolic blood pressure (DBP) of the patients. No statistically significant differences were observed in the improvement of glycosylated hemoglobin (HbA1c) and triglyceride (TG) between the TRT-treated patients and placebo controls. The results of Egger's and Begg's tests showed no significant publication bias among the studies.TRT can significantly improve metabolic indexes in patients with hypogonadism, though further studies are needed to confirm its long-term efficacy and safety in patients with metabolic disorders." @default.
- W4387661917 created "2023-10-17" @default.
- W4387661917 creator A5033089578 @default.
- W4387661917 creator A5036065682 @default.
- W4387661917 creator A5043492103 @default.
- W4387661917 creator A5046597133 @default.
- W4387661917 creator A5047881540 @default.
- W4387661917 creator A5075610939 @default.
- W4387661917 creator A5084906854 @default.
- W4387661917 date "2022-10-01" @default.
- W4387661917 modified "2023-10-17" @default.
- W4387661917 title "[Testosterone replacement therapy improves metabolic indexes of the patients with hypogonadism: A meta-analysis]." @default.
- W4387661917 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37838960" @default.
- W4387661917 hasPublicationYear "2022" @default.
- W4387661917 type Work @default.
- W4387661917 citedByCount "0" @default.
- W4387661917 crossrefType "journal-article" @default.
- W4387661917 hasAuthorship W4387661917A5033089578 @default.
- W4387661917 hasAuthorship W4387661917A5036065682 @default.
- W4387661917 hasAuthorship W4387661917A5043492103 @default.
- W4387661917 hasAuthorship W4387661917A5046597133 @default.
- W4387661917 hasAuthorship W4387661917A5047881540 @default.
- W4387661917 hasAuthorship W4387661917A5075610939 @default.
- W4387661917 hasAuthorship W4387661917A5084906854 @default.
- W4387661917 hasConcept C126322002 @default.
- W4387661917 hasConcept C134018914 @default.
- W4387661917 hasConcept C142724271 @default.
- W4387661917 hasConcept C168563851 @default.
- W4387661917 hasConcept C204787440 @default.
- W4387661917 hasConcept C27081682 @default.
- W4387661917 hasConcept C2776193436 @default.
- W4387661917 hasConcept C2776478404 @default.
- W4387661917 hasConcept C2777391703 @default.
- W4387661917 hasConcept C2778163477 @default.
- W4387661917 hasConcept C2778535154 @default.
- W4387661917 hasConcept C2778913445 @default.
- W4387661917 hasConcept C2779279991 @default.
- W4387661917 hasConcept C2779306644 @default.
- W4387661917 hasConcept C2780221984 @default.
- W4387661917 hasConcept C2780439572 @default.
- W4387661917 hasConcept C2780578515 @default.
- W4387661917 hasConcept C511355011 @default.
- W4387661917 hasConcept C71924100 @default.
- W4387661917 hasConcept C84393581 @default.
- W4387661917 hasConcept C90924648 @default.
- W4387661917 hasConcept C95190672 @default.
- W4387661917 hasConceptScore W4387661917C126322002 @default.
- W4387661917 hasConceptScore W4387661917C134018914 @default.
- W4387661917 hasConceptScore W4387661917C142724271 @default.
- W4387661917 hasConceptScore W4387661917C168563851 @default.
- W4387661917 hasConceptScore W4387661917C204787440 @default.
- W4387661917 hasConceptScore W4387661917C27081682 @default.
- W4387661917 hasConceptScore W4387661917C2776193436 @default.
- W4387661917 hasConceptScore W4387661917C2776478404 @default.
- W4387661917 hasConceptScore W4387661917C2777391703 @default.
- W4387661917 hasConceptScore W4387661917C2778163477 @default.
- W4387661917 hasConceptScore W4387661917C2778535154 @default.
- W4387661917 hasConceptScore W4387661917C2778913445 @default.
- W4387661917 hasConceptScore W4387661917C2779279991 @default.
- W4387661917 hasConceptScore W4387661917C2779306644 @default.
- W4387661917 hasConceptScore W4387661917C2780221984 @default.
- W4387661917 hasConceptScore W4387661917C2780439572 @default.
- W4387661917 hasConceptScore W4387661917C2780578515 @default.
- W4387661917 hasConceptScore W4387661917C511355011 @default.
- W4387661917 hasConceptScore W4387661917C71924100 @default.
- W4387661917 hasConceptScore W4387661917C84393581 @default.
- W4387661917 hasConceptScore W4387661917C90924648 @default.
- W4387661917 hasConceptScore W4387661917C95190672 @default.
- W4387661917 hasIssue "10" @default.
- W4387661917 hasLocation W43876619171 @default.
- W4387661917 hasOpenAccess W4387661917 @default.
- W4387661917 hasPrimaryLocation W43876619171 @default.
- W4387661917 hasRelatedWork W1991965293 @default.
- W4387661917 hasRelatedWork W2016457277 @default.
- W4387661917 hasRelatedWork W2057501204 @default.
- W4387661917 hasRelatedWork W2110332595 @default.
- W4387661917 hasRelatedWork W2117018656 @default.
- W4387661917 hasRelatedWork W2253220613 @default.
- W4387661917 hasRelatedWork W2376494475 @default.
- W4387661917 hasRelatedWork W2521243952 @default.
- W4387661917 hasRelatedWork W3011015268 @default.
- W4387661917 hasRelatedWork W4292848291 @default.
- W4387661917 hasVolume "28" @default.
- W4387661917 isParatext "false" @default.
- W4387661917 isRetracted "false" @default.
- W4387661917 workType "article" @default.