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- W4387666987 abstract "Researchers who use nanopore-based DNA sequencing devices are scratching their heads over a recent announcement from Oxford Nanopore Technologies (ONT) that its flow cells work better in the dark. The devices sequence nucleic acids by detecting changes in current as DNA or RNA strands file through protein pores, which were not previously thought to be light sensitive. Yet the company says in a user community post that shielding a flow cell from light can yield increases in data output that vary according to the length of DNA to be sequenced and the version of the technology used. ONT reports increases in sequence output ranging from 11% for long molecules read by an older-generation flow cell to a staggering 469% for short molecules read by a newer pore. It is not yet clear how light affects the system. ONT did not respond to an interview request, but in a post to" @default.
- W4387666987 created "2023-10-17" @default.
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- W4387666987 date "2023-10-16" @default.
- W4387666987 modified "2023-10-17" @default.
- W4387666987 title "A nanopore light sensitivity puzzle" @default.
- W4387666987 doi "https://doi.org/10.1021/cen-10134-scicon2" @default.
- W4387666987 hasPublicationYear "2023" @default.
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