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- W4387668082 abstract "Glycans on the surface of bacteria have diverse and essential biological functions and have widely been employed for treating various bacterial infectious diseases. Furthermore, these glycans comprise various functional groups, such as O-, N-, and carboxyl-modified, which significantly increase the diversity of glycan structures. These functional groups are not only crucial for glycans’ structural identity but are also essential for their biological functions. Therefore, a clear understanding of the biological functions of these modified groups in corresponding bacterial glycans is crucial for their medical applications. Thus far, the activities of functional groups in some biomedical active carbohydrates have been elucidated. It has been shown that some functional groups are key constituents of biologically active bacterial glycans, while others are actually not essential and may even mask the functions of the glycans. This paper reviews the structures of naturally occurring side-chain functional groups in glycans located on the bacterial surface and their roles in immunological responses." @default.
- W4387668082 created "2023-10-17" @default.
- W4387668082 creator A5007022127 @default.
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- W4387668082 creator A5049527131 @default.
- W4387668082 creator A5056546581 @default.
- W4387668082 creator A5074859921 @default.
- W4387668082 date "2023-10-16" @default.
- W4387668082 modified "2023-10-17" @default.
- W4387668082 title "Effect of Side-Chain Functional Groups in the Immunogenicity of Bacterial Surface Glycans" @default.
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