FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387669934> ?p ?o ?g. }

• W4387669934 endingPage "e16259" @default.
• W4387669934 startingPage "e16259" @default.
• W4387669934 abstract "The entomopathogenic fungus Culicinomyces clavisporus is known to infect and kill mosquito larvae and therefore has been seen as a potential biological control agent against disease vector mosquitoes. Whereas most fungal entomopathogens infect hosts by penetrating the external cuticle, C. clavisporus initiates infection through ingestion ( per o s). This unique infection strategy suggests that the C. clavisporus genome may be mined for novel pathogenicity factors with potential for vector control. To this end, an Isoseq-based transcriptome analysis was initiated, and resulted in a total of 3,512,145 sequences, with an average length of 1,732 bp. Transcripts assembly and annotation suggested that the C. clavisporus transcriptome lacked the cuticle-degrading proteins that have been associated with other entomopathogenic fungi, supporting the per os pathogenicity process. Furthermore, mining of the sequence data unexpectedly revealed C. clavisporus transcripts homologous to the Hirsutellin toxin. Comparative sequence analyses indicated that the C. clavisporus Hirsutellin predicted protein has retained the canonical molecular features that have been associated with the ribotoxic and insecticidal properties of the original toxin isolated from Hirsutella thompsonii . The identification of an Hirsutellin ortholog in C. clavisporus was supported by phylogenetic analyses demonstrating that Culicinomyces and Hirsutella were closely related genera in the Ophiocordycipitaceae family. Validation of the mosquitocidal activity of this novel C. clavisporus protein has yet to be performed but may help position Hirsutellin orthologs as prime candidates for the development of alternative biocontrol approaches complementing the current toolbox of vector mosquito management strategies." @default.
• W4387669934 created "2023-10-17" @default.
• W4387669934 creator A5013831730 @default.
• W4387669934 creator A5093069985 @default.
• W4387669934 date "2023-10-16" @default.
• W4387669934 modified "2023-10-17" @default.
• W4387669934 title "The transcriptome of the entomopathogenic fungus <i>Culicinomyces clavisporus</i> contains an ortholog of the insecticidal ribotoxin Hirsutellin" @default.
• W4387669934 cites W14860267 @default.
• W4387669934 cites W1966317578 @default.
• W4387669934 cites W1974116356 @default.
• W4387669934 cites W1975945444 @default.
• W4387669934 cites W1990181264 @default.
• W4387669934 cites W1995880287 @default.
• W4387669934 cites W1998686218 @default.
• W4387669934 cites W2003734402 @default.
• W4387669934 cites W2007917334 @default.
• W4387669934 cites W2009468103 @default.
• W4387669934 cites W2018477907 @default.
• W4387669934 cites W2021393344 @default.
• W4387669934 cites W2023764387 @default.
• W4387669934 cites W2046889205 @default.
• W4387669934 cites W2048505667 @default.
• W4387669934 cites W2071989686 @default.
• W4387669934 cites W2079202518 @default.
• W4387669934 cites W2085784667 @default.
• W4387669934 cites W2097606916 @default.
• W4387669934 cites W2101295526 @default.
• W4387669934 cites W2105112523 @default.
• W4387669934 cites W2117540003 @default.
• W4387669934 cites W2117980392 @default.
• W4387669934 cites W2131368361 @default.
• W4387669934 cites W2132926880 @default.
• W4387669934 cites W2165328612 @default.
• W4387669934 cites W2220217038 @default.
• W4387669934 cites W2280220883 @default.
• W4387669934 cites W2302139368 @default.
• W4387669934 cites W2322525673 @default.
• W4387669934 cites W2332867031 @default.
• W4387669934 cites W2339267119 @default.
• W4387669934 cites W2340245717 @default.
• W4387669934 cites W2522639609 @default.
• W4387669934 cites W2529742372 @default.
• W4387669934 cites W2591266398 @default.
• W4387669934 cites W2602102497 @default.
• W4387669934 cites W2799524357 @default.
• W4387669934 cites W2803031838 @default.
• W4387669934 cites W2904020092 @default.
• W4387669934 cites W2939116936 @default.
• W4387669934 cites W2979519051 @default.
• W4387669934 cites W3001951030 @default.
• W4387669934 cites W3014857781 @default.
• W4387669934 cites W3032668905 @default.
• W4387669934 cites W3156458251 @default.
• W4387669934 cites W3217216416 @default.
• W4387669934 cites W4206950245 @default.
• W4387669934 cites W4234443522 @default.
• W4387669934 cites W4319460878 @default.
• W4387669934 cites W2046393003 @default.
• W4387669934 doi "https://doi.org/10.7717/peerj.16259" @default.
• W4387669934 hasPublicationYear "2023" @default.
• W4387669934 type Work @default.
• W4387669934 citedByCount "0" @default.
• W4387669934 crossrefType "journal-article" @default.
• W4387669934 hasAuthorship W4387669934A5013831730 @default.
• W4387669934 hasAuthorship W4387669934A5093069985 @default.
• W4387669934 hasBestOaLocation W43876699341 @default.
• W4387669934 hasConcept C104317684 @default.
• W4387669934 hasConcept C104727253 @default.
• W4387669934 hasConcept C141231307 @default.
• W4387669934 hasConcept C150194340 @default.
• W4387669934 hasConcept C162317418 @default.
• W4387669934 hasConcept C193252679 @default.
• W4387669934 hasConcept C2775961707 @default.
• W4387669934 hasConcept C2779678110 @default.
• W4387669934 hasConcept C2781391353 @default.
• W4387669934 hasConcept C54355233 @default.
• W4387669934 hasConcept C59822182 @default.
• W4387669934 hasConcept C86803240 @default.
• W4387669934 hasConcept C89423630 @default.
• W4387669934 hasConceptScore W4387669934C104317684 @default.
• W4387669934 hasConceptScore W4387669934C104727253 @default.
• W4387669934 hasConceptScore W4387669934C141231307 @default.
• W4387669934 hasConceptScore W4387669934C150194340 @default.
• W4387669934 hasConceptScore W4387669934C162317418 @default.
• W4387669934 hasConceptScore W4387669934C193252679 @default.
• W4387669934 hasConceptScore W4387669934C2775961707 @default.
• W4387669934 hasConceptScore W4387669934C2779678110 @default.
• W4387669934 hasConceptScore W4387669934C2781391353 @default.
• W4387669934 hasConceptScore W4387669934C54355233 @default.
• W4387669934 hasConceptScore W4387669934C59822182 @default.
• W4387669934 hasConceptScore W4387669934C86803240 @default.
• W4387669934 hasConceptScore W4387669934C89423630 @default.
• W4387669934 hasLocation W43876699341 @default.
• W4387669934 hasOpenAccess W4387669934 @default.
• W4387669934 hasPrimaryLocation W43876699341 @default.
• W4387669934 hasRelatedWork W2028462563 @default.
• W4387669934 hasRelatedWork W2130162427 @default.
• W4387669934 hasRelatedWork W2392100801 @default.

• next