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- W4387675248 abstract "Prion diseases are relatively rare, transmissible, progressive, and eventually fatal. Examples include Creutzfeldt-Jakob disease (CJD) and fatal insomnia. In humans, CJD is the most common prion disease and may be sporadic, familial, or acquired. Memory loss and confusion may be followed by ataxia, incoordination, myoclonus, hallucinations, neuropathy, seizures, and movement disorders. Fatal insomnia is extremely rare, in which there is degenerative nerve disease that causes increasingly worsening problems with sleep. Eventually there is physical and mental deterioration. Gerstmann-Sträussler-Scheinker (GSS) disease is a very rare neurodegenerative brain disorder that begins with ataxia, dementia, encephalopathy, balance problems, difficulty walking, incoordination, and multicentric prior protein plaques. Generally, prion diseases develop during adulthood, with CJD being fatal in 100% of cases. Death usually occurs within 6–12 months, usually due to pneumonia. Fatal insomnia has a prognosis based on stage and symptom severity, and GSS disease is usually fatal within 5 years." @default.
- W4387675248 created "2023-10-17" @default.
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- W4387675248 date "2023-01-01" @default.
- W4387675248 modified "2023-10-17" @default.
- W4387675248 title "Prion diseases" @default.
- W4387675248 doi "https://doi.org/10.1016/b978-0-323-95901-8.00026-2" @default.
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