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- W43920943 abstract "Publisher Summary This chapter focuses on the effects of neuropeptides on glucoregulation. The discovery of neuropeptides and the observations of the effects on glucoregulation have developed a new field in the study of carbohydrate metabolism. The chapter discusses that it is not clear whether the peptides act as hormones in the classical sense, as neurotransmitters from nerve endings, or as local mediators of cell-to-cell interactions with regard to the peripheral actions of the peptides on glucoregulation. Among all other neuropeptides, bombesin, β -endorphin, somatostatin, thyroid-releasing hormone (TRH), and CCK-8 have been reported to act within the central nervous system (CNS) with regard to glucoregulation. Bombesin and somatostatin revealed significant changes in plasma glucose of the hepatic vein after injection into the ventromedial hypothalamus (VMH), lateral hypothalamus (LH), and third ventricle, respectively. This suggests that the action site of these peptides might be distributed throughout or beyond the hypothalamus. Other peptides injected into VMH or LH did not reveal any significant changes in hepatic plasma glucose concentrations." @default.
- W43920943 created "2016-06-24" @default.
- W43920943 creator A5040641756 @default.
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- W43920943 date "1983-01-01" @default.
- W43920943 modified "2023-10-18" @default.
- W43920943 title "The Effects of Neuropeptides on Glucoregulation" @default.
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