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- W44153114 endingPage "290" @default.
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- W44153114 abstract "Among the different classes of drugs used in the treatment of asthma, the bronchodilators (β2-adrenoceptor agonists, muscarinic receptor antagonists, methylxanthines) bring symptomatic relief but contribute little to ameliorating the underlying bronchial inflammation. Glucocorticoids (see Chap. 8) exert a potent antiinflammatory effect and, particularly when inhaled, have both therapeutic and prophylactic value. The drug that is now accepted clinically as having a prophylactic effect in asthma, whilst only rarely bringing symptomatic relief, is cromoglycate; the recently introduced nedocromil is another example of the same class of compound. Ketotifen has a different pharmacological profile and has gained some acceptance as a prophylactic agent in asthma. This chapter will only review the pharmacology of drugs in clinical use (cromoglycate, nedocromil, ketotifen), although there is much current research directed towards finding other new types of antiinflammatory agents to be used as first-line durgs in mild asthma, leaving glucocorticoids for treatment of severe asthma." @default.
- W44153114 created "2016-06-24" @default.
- W44153114 creator A5091683165 @default.
- W44153114 date "1991-01-01" @default.
- W44153114 modified "2023-09-27" @default.
- W44153114 title "Pharmacology of Prophylactic Anti-Asthma Drugs" @default.
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