Matches in SemOpenAlex for { <https://semopenalex.org/work/W4419979> ?p ?o ?g. }
Showing items 1 to 70 of
70
with 100 items per page.
- W4419979 endingPage "81" @default.
- W4419979 startingPage "78" @default.
- W4419979 abstract "Over a period of nine months twenty-five epileptic patients were treated with the oral loading dose of phenytoin. The dose ranged from 12 to 23 mg/kg body weight during 1 to 12 hours. In 20 patients with serial seizures or intolerance to other antiepileptic drugs this treatment was effective. Seizures also stopped in 2 of 4 patients with serial partial motor seizures. These 2 patients required both higher loading dose and faster rate of administration than the other patients. A patient with epilepsia partialis continua failed to respond to the treatment. Patients that received phenytoin through the naso-gastric tube, in respect to oral administration, required higher doses to obtain therapeutic plasma levels of phenytoin. One patient had mild nausea, 3 mild dizziness, and 1 tinitus on the first day of the treatment. There was no correlation between a given dose and the achieved phenytoin plasma levels. In our opinion the therapy with oral loading dose of phenytoin is highly effective in the treatment of serial generalized seizures and rapid antiepileptic drug substitution, and partially effective in the prevention of partial motor seizures. It produces only mild and transient side-effects." @default.
- W4419979 created "2016-06-24" @default.
- W4419979 creator A5009826939 @default.
- W4419979 creator A5082550137 @default.
- W4419979 date "1994-03-01" @default.
- W4419979 modified "2023-09-23" @default.
- W4419979 title "[Oral loading dose of phenytoin in the treatment of serial seizures, prevention of seizure recurrence and rapid drug substitution]." @default.
- W4419979 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17972815" @default.
- W4419979 hasPublicationYear "1994" @default.
- W4419979 type Work @default.
- W4419979 sameAs 4419979 @default.
- W4419979 citedByCount "0" @default.
- W4419979 crossrefType "journal-article" @default.
- W4419979 hasAuthorship W4419979A5009826939 @default.
- W4419979 hasAuthorship W4419979A5082550137 @default.
- W4419979 hasConcept C118552586 @default.
- W4419979 hasConcept C2775858608 @default.
- W4419979 hasConcept C2777056448 @default.
- W4419979 hasConcept C2778062832 @default.
- W4419979 hasConcept C2778186239 @default.
- W4419979 hasConcept C2778337148 @default.
- W4419979 hasConcept C2780035454 @default.
- W4419979 hasConcept C2780580376 @default.
- W4419979 hasConcept C2780852908 @default.
- W4419979 hasConcept C42219234 @default.
- W4419979 hasConcept C71924100 @default.
- W4419979 hasConcept C98274493 @default.
- W4419979 hasConceptScore W4419979C118552586 @default.
- W4419979 hasConceptScore W4419979C2775858608 @default.
- W4419979 hasConceptScore W4419979C2777056448 @default.
- W4419979 hasConceptScore W4419979C2778062832 @default.
- W4419979 hasConceptScore W4419979C2778186239 @default.
- W4419979 hasConceptScore W4419979C2778337148 @default.
- W4419979 hasConceptScore W4419979C2780035454 @default.
- W4419979 hasConceptScore W4419979C2780580376 @default.
- W4419979 hasConceptScore W4419979C2780852908 @default.
- W4419979 hasConceptScore W4419979C42219234 @default.
- W4419979 hasConceptScore W4419979C71924100 @default.
- W4419979 hasConceptScore W4419979C98274493 @default.
- W4419979 hasLocation W44199791 @default.
- W4419979 hasLocation W44199792 @default.
- W4419979 hasOpenAccess W4419979 @default.
- W4419979 hasPrimaryLocation W44199791 @default.
- W4419979 hasRelatedWork W1511101368 @default.
- W4419979 hasRelatedWork W175760129 @default.
- W4419979 hasRelatedWork W1980394556 @default.
- W4419979 hasRelatedWork W1998340140 @default.
- W4419979 hasRelatedWork W2014192828 @default.
- W4419979 hasRelatedWork W2047609248 @default.
- W4419979 hasRelatedWork W2048791185 @default.
- W4419979 hasRelatedWork W2052227537 @default.
- W4419979 hasRelatedWork W2081445438 @default.
- W4419979 hasRelatedWork W2093676036 @default.
- W4419979 hasRelatedWork W2115513910 @default.
- W4419979 hasRelatedWork W2182099291 @default.
- W4419979 hasRelatedWork W2239437636 @default.
- W4419979 hasRelatedWork W2404921217 @default.
- W4419979 hasRelatedWork W2406510102 @default.
- W4419979 hasRelatedWork W2430242636 @default.
- W4419979 hasRelatedWork W2430496805 @default.
- W4419979 hasRelatedWork W2501749187 @default.
- W4419979 hasRelatedWork W2728557852 @default.
- W4419979 hasRelatedWork W32075591 @default.
- W4419979 hasVolume "122" @default.
- W4419979 isParatext "false" @default.
- W4419979 isRetracted "false" @default.
- W4419979 magId "4419979" @default.
- W4419979 workType "article" @default.