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- W44757180 abstract "There is increasing experimental evidence that the critical molecule in radiobiology is the DNA double helix. Recently a molecular theory has been developed starting from the assumption that double strand breaks in the DNA are the most critical lesions for cell killing. This theory is applied to all types of ionizing radiation and thus neutrons as well as gamma or x radiation are assumed to cause the same type of primary damage. The difference between the neutron and gamma radiation effect is explained in the theory, by the different way in which these radiations induce the double strand breaks. Another biological end point that can be associated with damage to the DNA in a cell is a somatic mutation. If it is assuaned that a DNA double strand break is the most critical radiation induced lesion that can lead to a somatic mutation, a general equation can be derived for the induction of mutations by radiation. The theoretical equations are compared with data in the literature for neutron and gamma or x radiation for the two phenomena. The implications of the theoretical considerations for plant mutation breeding and the sterile male technique are discussed with respect to the optimalization ofmore » the required process. (GE)« less" @default.
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- W44757180 date "1973-01-01" @default.
- W44757180 modified "2023-09-27" @default.
- W44757180 title "Theoretical analysis of radiation sensitivity in cells following neutron irradiation" @default.
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