Matches in SemOpenAlex for { <https://semopenalex.org/work/W44951775> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W44951775 endingPage "119" @default.
- W44951775 startingPage "99" @default.
- W44951775 abstract "The application of SNP array technology to the analysis of cancer genomes has greatly advanced our knowledge of the incidence and functional consequences of acquired genomic copy number aberrations (aCNA) and LOH in various malignancies. The major challenges of using SNP arrays are accurately identifying acquired genomic DNA aberrations in the raw array data with very high sensitivity and specificity and meaningfully assessing the associations between these aberrations and biological characteristics or patient outcomes. Critical to the success and valid interpretation of data derived from SNP array profiling are (1) the purity of cells used as a source of template DNA; (2) the analysis of paired DNA samples (tumor and normal); (3) use of validated software tools for data analysis; (4) access to an acceptable gold standard for aCNA and LOH, including FISH data, cytogenetic results, and Q-PCR data; and (5) statistical support to employ or develop algorithmic approaches to SNP array data analysis. Overcalling of lesions including lack of validation and undercalling of lesions that display low fractional allelic representations are common problems. This guide should help the reader establish this powerful technology in the laboratory and aims to stimulate transition of SNP array profiling into clinical applications." @default.
- W44951775 created "2016-06-24" @default.
- W44951775 creator A5002639476 @default.
- W44951775 creator A5013706483 @default.
- W44951775 creator A5022598327 @default.
- W44951775 creator A5086477374 @default.
- W44951775 date "2013-01-01" @default.
- W44951775 modified "2023-09-23" @default.
- W44951775 title "Analysis of Acquired Genomic Copy Number Aberrations and Regions of Loss of Heterozygosity in Acute Myelogenous Leukemia Genomes Using Affymetrix SNP 6.0 Arrays and Supporting Software Tools" @default.
- W44951775 cites W196819375 @default.
- W44951775 cites W1977052779 @default.
- W44951775 cites W1984065010 @default.
- W44951775 cites W1988615111 @default.
- W44951775 cites W1994924914 @default.
- W44951775 cites W2010855093 @default.
- W44951775 cites W2023369015 @default.
- W44951775 cites W2038437697 @default.
- W44951775 cites W2039234691 @default.
- W44951775 cites W2040948620 @default.
- W44951775 cites W2054744711 @default.
- W44951775 cites W2065141457 @default.
- W44951775 cites W2110227850 @default.
- W44951775 cites W2145642574 @default.
- W44951775 cites W2156760370 @default.
- W44951775 cites W2163688965 @default.
- W44951775 doi "https://doi.org/10.1007/978-1-62703-281-0_7" @default.
- W44951775 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23412786" @default.
- W44951775 hasPublicationYear "2013" @default.
- W44951775 type Work @default.
- W44951775 sameAs 44951775 @default.
- W44951775 citedByCount "2" @default.
- W44951775 countsByYear W449517752013 @default.
- W44951775 countsByYear W449517752019 @default.
- W44951775 crossrefType "book-chapter" @default.
- W44951775 hasAuthorship W44951775A5002639476 @default.
- W44951775 hasAuthorship W44951775A5013706483 @default.
- W44951775 hasAuthorship W44951775A5022598327 @default.
- W44951775 hasAuthorship W44951775A5086477374 @default.
- W44951775 hasConcept C104317684 @default.
- W44951775 hasConcept C120821319 @default.
- W44951775 hasConcept C122060243 @default.
- W44951775 hasConcept C135763542 @default.
- W44951775 hasConcept C139275648 @default.
- W44951775 hasConcept C141231307 @default.
- W44951775 hasConcept C143589142 @default.
- W44951775 hasConcept C153209595 @default.
- W44951775 hasConcept C166608930 @default.
- W44951775 hasConcept C180754005 @default.
- W44951775 hasConcept C189206191 @default.
- W44951775 hasConcept C54355233 @default.
- W44951775 hasConcept C70721500 @default.
- W44951775 hasConcept C86803240 @default.
- W44951775 hasConceptScore W44951775C104317684 @default.
- W44951775 hasConceptScore W44951775C120821319 @default.
- W44951775 hasConceptScore W44951775C122060243 @default.
- W44951775 hasConceptScore W44951775C135763542 @default.
- W44951775 hasConceptScore W44951775C139275648 @default.
- W44951775 hasConceptScore W44951775C141231307 @default.
- W44951775 hasConceptScore W44951775C143589142 @default.
- W44951775 hasConceptScore W44951775C153209595 @default.
- W44951775 hasConceptScore W44951775C166608930 @default.
- W44951775 hasConceptScore W44951775C180754005 @default.
- W44951775 hasConceptScore W44951775C189206191 @default.
- W44951775 hasConceptScore W44951775C54355233 @default.
- W44951775 hasConceptScore W44951775C70721500 @default.
- W44951775 hasConceptScore W44951775C86803240 @default.
- W44951775 hasLocation W449517751 @default.
- W44951775 hasLocation W449517752 @default.
- W44951775 hasOpenAccess W44951775 @default.
- W44951775 hasPrimaryLocation W449517751 @default.
- W44951775 hasRelatedWork W1991988066 @default.
- W44951775 hasRelatedWork W2023767508 @default.
- W44951775 hasRelatedWork W2025820412 @default.
- W44951775 hasRelatedWork W2050489856 @default.
- W44951775 hasRelatedWork W2077969253 @default.
- W44951775 hasRelatedWork W2230923754 @default.
- W44951775 hasRelatedWork W2398718997 @default.
- W44951775 hasRelatedWork W2580965687 @default.
- W44951775 hasRelatedWork W2589989126 @default.
- W44951775 hasRelatedWork W2619697957 @default.
- W44951775 isParatext "false" @default.
- W44951775 isRetracted "false" @default.
- W44951775 magId "44951775" @default.
- W44951775 workType "book-chapter" @default.