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- W45092523 abstract "The use of high-dose chemotherapy and autologous bone marrow transplantation (ABMT) for the treatment of relapsed or high-risk lymphoid malignancies has now been demonstrated to result in long-term disease-free survival in a number of patients [1-4]. However, severe and prolonged neutropenia can lead to infectious complications which can be fatal in a number of cases. The routine use of myeloid hematopoietic growth factors such as granulocyte-macrophage colony-stimulating factor (GM-CSF) and granulocyte colony-stimulating factor (GM-CSF) and granulocyte colony-stimulating factor (G-CSF) post ABMT have now been documented in several phase III trials to decrease the neutropenic period and number of infectious complications [5-8]. However, thrombocytopenia post ABMT remains a clinical problem with the administration of currently available GM-CSF or G-CSF not affecting the time to platelet transfusion independence." @default.
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- W45092523 date "1997-01-01" @default.
- W45092523 modified "2023-09-30" @default.
- W45092523 title "Initial Trial of PIXY 321 Following Autologous Bone Marrow Transplantation" @default.
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- W45092523 doi "https://doi.org/10.1007/978-3-642-60377-8_74" @default.
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