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- W45127957 abstract "Transcranial magnetic stimulation (TMS) over the motor cortex during motor imagery results in increased amplitudes of motor evoked potentials (MEPs) in muscles specific to the imagined movement. Functional MRI studies demonstrate that motor imagery involves a widespread neural network including prefrontal and parietal areas. The purpose of this pilot TMS study was to explore whether the left prefrontal cortex (PFC) is an active part of the motor imagery network. MEPs were recorded in 5 healthy subjects in tibialis anterior (TA) muscles during the imagined right ankle dorsiflexion while the neural processes in the left PFC were disturbed by a single TMS pulse 300ms prior to the leg area stimulation with TMS. Motor imagery alone significantly increased MEP amplitudes in the target TA muscle compared to rest(440% on average, p=0.004). The left PFC stimulation prior to test stimulus significantly reduced the facilitation of MEPs during motor imagery (326%, p=0.031) butleft PFC stimulation had no effect when delivered during rest (103%). This suggests a functional link between the left PFC and sensorimotor cortex actively involved in motor imagery. Appropriately timed TMS over the left PCF most likely disturbed the kinesthetic working memory required for maintaining motor imagery." @default.
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- W45127957 date "2013-01-01" @default.
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- W45127957 title "Left Prefrontal Cortex Contributes to Motor Imagery: A Pilot Study" @default.
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- W45127957 doi "https://doi.org/10.5923/j.neuroscience.20130202.01" @default.
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