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- W45131436 abstract "Pancreatic cancer (PC) is the fourth leading cause of cancer-related death in western societies, including the United Kingdom, and has a 5-year survival of <5%. Recent large-scale genomic sequencing efforts suggest that, apart from a few that cannot be effectively targeted, mutations occur at a rate of less than 2%, making PC one of the most genomically diverse cancers. This heterogeneity may explain the multiple failed chemotherapeutic trials in the past; at the least, it creates an opportunity to explore a stratified approach based on molecular phenotype. In this chapter, we examine existing evidence and explore a potential stratified approach for PC treatment." @default.
- W45131436 created "2016-06-24" @default.
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- W45131436 date "2014-01-01" @default.
- W45131436 modified "2023-09-25" @default.
- W45131436 title "Stratified Medicine for Pancreatic Cancer" @default.
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- W45131436 doi "https://doi.org/10.1016/b978-0-12-386882-4.00034-7" @default.
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