FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W45365868> ?p ?o ?g. }

• W45365868 endingPage "C2062" @default.
• W45365868 startingPage "C2049" @default.
• W45365868 abstract "Infusion of 13C-labeled lactate into rabbits and the subsequent measurement of glutamate isotopomers by 13C nuclear magnetic resonance (NMR) spectroscopy enables one to calculate relative flow rates associated with the tricarboxylic acid (TCA) cycle, albeit with a lower precision than one would obtain using a perfused organ. Two factors contribute to the lower precision in the determination of relative flow rates for the in vivo system: 1) a poorly defined pyruvate input and 2) low levels of 13C-enriched oxaloacetate and acetyl-CoA isotopomers, which give rise to weaker glutamate isotopomer NMR signals. To help overcome these limitations, we introduce a procedure to 1) include experimental data from gas chromatography-mass spectrometry (GC-MS) and 2) account for the uncertainty in the labeling of the input to pyruvate by creating the labeling as a measurement that is subject to measurement error. The effects of the uncertainties in the input labeling, NMR data, and MS data are evaluated via a Monte Carlo method. The change in the precision of the relative fluxes for the cases of high/low NMR and high/low MS precision is given. An uncertainty in the lactate measurements of up to 10% does not add significantly to the imprecision of the relative flow rates." @default.
• W45365868 created "2016-06-24" @default.
• W45365868 creator A5008085561 @default.
• W45365868 creator A5020257591 @default.
• W45365868 creator A5044793226 @default.
• W45365868 creator A5053450104 @default.
• W45365868 creator A5058901029 @default.
• W45365868 creator A5059731538 @default.
• W45365868 creator A5065140177 @default.
• W45365868 date "1997-06-01" @default.
• W45365868 modified "2023-10-03" @default.
• W45365868 title "TCA cycle flux estimates from NMR- and GC-MS-determined [13C]glutamate isotopomers in liver" @default.
• W45365868 cites W1515415221 @default.
• W45365868 cites W1542238138 @default.
• W45365868 cites W1574117447 @default.
• W45365868 cites W1853709930 @default.
• W45365868 cites W2007727338 @default.
• W45365868 cites W2012361529 @default.
• W45365868 cites W2018844109 @default.
• W45365868 cites W2043844351 @default.
• W45365868 cites W2044574043 @default.
• W45365868 cites W2055655374 @default.
• W45365868 cites W2077911717 @default.
• W45365868 cites W4317649971 @default.
• W45365868 doi "https://doi.org/10.1152/ajpcell.1997.272.6.c2049" @default.
• W45365868 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9227434" @default.
• W45365868 hasPublicationYear "1997" @default.
• W45365868 type Work @default.
• W45365868 sameAs 45365868 @default.
• W45365868 citedByCount "22" @default.
• W45365868 countsByYear W453658682012 @default.
• W45365868 countsByYear W453658682013 @default.
• W45365868 countsByYear W453658682016 @default.
• W45365868 countsByYear W453658682017 @default.
• W45365868 countsByYear W453658682020 @default.
• W45365868 countsByYear W453658682022 @default.
• W45365868 countsByYear W453658682023 @default.
• W45365868 crossrefType "journal-article" @default.
• W45365868 hasAuthorship W45365868A5008085561 @default.
• W45365868 hasAuthorship W45365868A5020257591 @default.
• W45365868 hasAuthorship W45365868A5044793226 @default.
• W45365868 hasAuthorship W45365868A5053450104 @default.
• W45365868 hasAuthorship W45365868A5058901029 @default.
• W45365868 hasAuthorship W45365868A5059731538 @default.
• W45365868 hasAuthorship W45365868A5065140177 @default.
• W45365868 hasConcept C113196181 @default.
• W45365868 hasConcept C121332964 @default.
• W45365868 hasConcept C127124265 @default.
• W45365868 hasConcept C160941953 @default.
• W45365868 hasConcept C164304813 @default.
• W45365868 hasConcept C165135838 @default.
• W45365868 hasConcept C170493617 @default.
• W45365868 hasConcept C178790620 @default.
• W45365868 hasConcept C185544564 @default.
• W45365868 hasConcept C185592680 @default.
• W45365868 hasConcept C2776441662 @default.
• W45365868 hasConcept C32909587 @default.
• W45365868 hasConcept C43617362 @default.
• W45365868 hasConcept C55493867 @default.
• W45365868 hasConcept C61174792 @default.
• W45365868 hasConcept C62231903 @default.
• W45365868 hasConcept C66974803 @default.
• W45365868 hasConcept C68709404 @default.
• W45365868 hasConcept C71240020 @default.
• W45365868 hasConceptScore W45365868C113196181 @default.
• W45365868 hasConceptScore W45365868C121332964 @default.
• W45365868 hasConceptScore W45365868C127124265 @default.
• W45365868 hasConceptScore W45365868C160941953 @default.
• W45365868 hasConceptScore W45365868C164304813 @default.
• W45365868 hasConceptScore W45365868C165135838 @default.
• W45365868 hasConceptScore W45365868C170493617 @default.
• W45365868 hasConceptScore W45365868C178790620 @default.
• W45365868 hasConceptScore W45365868C185544564 @default.
• W45365868 hasConceptScore W45365868C185592680 @default.
• W45365868 hasConceptScore W45365868C2776441662 @default.
• W45365868 hasConceptScore W45365868C32909587 @default.
• W45365868 hasConceptScore W45365868C43617362 @default.
• W45365868 hasConceptScore W45365868C55493867 @default.
• W45365868 hasConceptScore W45365868C61174792 @default.
• W45365868 hasConceptScore W45365868C62231903 @default.
• W45365868 hasConceptScore W45365868C66974803 @default.
• W45365868 hasConceptScore W45365868C68709404 @default.
• W45365868 hasConceptScore W45365868C71240020 @default.
• W45365868 hasIssue "6" @default.
• W45365868 hasLocation W453658681 @default.
• W45365868 hasLocation W453658682 @default.
• W45365868 hasOpenAccess W45365868 @default.
• W45365868 hasPrimaryLocation W453658681 @default.
• W45365868 hasRelatedWork W1997291244 @default.
• W45365868 hasRelatedWork W2010373805 @default.
• W45365868 hasRelatedWork W2031825920 @default.
• W45365868 hasRelatedWork W2049759143 @default.
• W45365868 hasRelatedWork W2084915868 @default.
• W45365868 hasRelatedWork W3132074972 @default.
• W45365868 hasRelatedWork W4213425988 @default.
• W45365868 hasRelatedWork W4315434045 @default.
• W45365868 hasRelatedWork W43845139 @default.
• W45365868 hasRelatedWork W4386070905 @default.

• next