Matches in SemOpenAlex for { <https://semopenalex.org/work/W4549392> ?p ?o ?g. }
- W4549392 endingPage "313" @default.
- W4549392 startingPage "287" @default.
- W4549392 abstract "Nuclear factor for IL-6 expression (NF-IL6) was originally identified as a nuclear factor binding to a 14-bp palindromic sequence (ACATTGCACAATCT) within an interleukin (IL)-1 responsive element in the human IL-6 gene (1). The cloning of the cDNA encoding human NF-IL6 revealed that it shows a high degree of homology with C/EBP in the carboxy-terminal basic and leucine zipper domains, responsible for DNA binding and dimerization, respectively (2). NF-IL6 recognizes the same nucleotide sequences as C/EBP. Both proteins bind to a variety of the divergent nucleotide sequences with different affinity, the consensus sequence is T(T/G)NNGNNAA(T/G). The NF-IL6 gene is intronless, and produces two proteins, liver-enriched transcriptional activator protein (LAP, equivalent to NF-IL6) and liver inhibitory protein (LIP) by alternative usage of two AUG initiation codons within the same open reading frame (3). LIP contains the DNA binding and dimerization domains but is devoid of the N terminal transcriptional activation domain, and therefore behaves as an antagonist of LAP-induced transcription." @default.
- W4549392 created "2016-06-24" @default.
- W4549392 creator A5018553332 @default.
- W4549392 creator A5021463605 @default.
- W4549392 creator A5064758344 @default.
- W4549392 date "1998-01-01" @default.
- W4549392 modified "2023-10-13" @default.
- W4549392 title "NF-IL6 Knockout Mice" @default.
- W4549392 cites W1486150850 @default.
- W4549392 cites W1516811209 @default.
- W4549392 cites W1526346536 @default.
- W4549392 cites W1739247159 @default.
- W4549392 cites W179818011 @default.
- W4549392 cites W1929330671 @default.
- W4549392 cites W1933156589 @default.
- W4549392 cites W1934337364 @default.
- W4549392 cites W1947030034 @default.
- W4549392 cites W1964842789 @default.
- W4549392 cites W1968424865 @default.
- W4549392 cites W1983683479 @default.
- W4549392 cites W1988059168 @default.
- W4549392 cites W1997739078 @default.
- W4549392 cites W2003124067 @default.
- W4549392 cites W2003798179 @default.
- W4549392 cites W2005019916 @default.
- W4549392 cites W2005484362 @default.
- W4549392 cites W2007409501 @default.
- W4549392 cites W2009046213 @default.
- W4549392 cites W2009550948 @default.
- W4549392 cites W2018233688 @default.
- W4549392 cites W2022308523 @default.
- W4549392 cites W2025505666 @default.
- W4549392 cites W2034200840 @default.
- W4549392 cites W2034856894 @default.
- W4549392 cites W2035616122 @default.
- W4549392 cites W2036602491 @default.
- W4549392 cites W2043913178 @default.
- W4549392 cites W2047842452 @default.
- W4549392 cites W2050283646 @default.
- W4549392 cites W2060912271 @default.
- W4549392 cites W2062472841 @default.
- W4549392 cites W2064541600 @default.
- W4549392 cites W2067761476 @default.
- W4549392 cites W2068871282 @default.
- W4549392 cites W2070538981 @default.
- W4549392 cites W2073132923 @default.
- W4549392 cites W2078853769 @default.
- W4549392 cites W2096440330 @default.
- W4549392 cites W2101127398 @default.
- W4549392 cites W2102411042 @default.
- W4549392 cites W2115086627 @default.
- W4549392 cites W2119577005 @default.
- W4549392 cites W2122515902 @default.
- W4549392 cites W2128673878 @default.
- W4549392 cites W2130524213 @default.
- W4549392 cites W2133353140 @default.
- W4549392 cites W2136066768 @default.
- W4549392 cites W2149232299 @default.
- W4549392 cites W215245711 @default.
- W4549392 cites W2153741820 @default.
- W4549392 cites W2166788322 @default.
- W4549392 cites W2168415166 @default.
- W4549392 cites W2170005346 @default.
- W4549392 cites W2182302387 @default.
- W4549392 cites W2270245312 @default.
- W4549392 cites W2298242819 @default.
- W4549392 cites W2400313130 @default.
- W4549392 cites W321874077 @default.
- W4549392 cites W619499661 @default.
- W4549392 cites W97264933 @default.
- W4549392 doi "https://doi.org/10.1007/978-1-4757-2753-1_17" @default.
- W4549392 hasPublicationYear "1998" @default.
- W4549392 type Work @default.
- W4549392 sameAs 4549392 @default.
- W4549392 citedByCount "0" @default.
- W4549392 crossrefType "journal-article" @default.
- W4549392 hasAuthorship W4549392A5018553332 @default.
- W4549392 hasAuthorship W4549392A5021463605 @default.
- W4549392 hasAuthorship W4549392A5064758344 @default.
- W4549392 hasConcept C104317684 @default.
- W4549392 hasConcept C153911025 @default.
- W4549392 hasConcept C156860981 @default.
- W4549392 hasConcept C167625842 @default.
- W4549392 hasConcept C187882448 @default.
- W4549392 hasConcept C29512474 @default.
- W4549392 hasConcept C47289529 @default.
- W4549392 hasConcept C54355233 @default.
- W4549392 hasConcept C84148353 @default.
- W4549392 hasConcept C86339819 @default.
- W4549392 hasConcept C86803240 @default.
- W4549392 hasConcept C88045685 @default.
- W4549392 hasConceptScore W4549392C104317684 @default.
- W4549392 hasConceptScore W4549392C153911025 @default.
- W4549392 hasConceptScore W4549392C156860981 @default.
- W4549392 hasConceptScore W4549392C167625842 @default.
- W4549392 hasConceptScore W4549392C187882448 @default.
- W4549392 hasConceptScore W4549392C29512474 @default.
- W4549392 hasConceptScore W4549392C47289529 @default.