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- W45542595 abstract "The acute-phase response (APR) refers to a large number of systemic and metabolic changes secondary to local inflammation following a wide variety of noxious stimuli. The principal stimuli that give rise to the APR are infection, surgical and other trauma, neoplasm, burn injury, tissue infarction, various inflammatory states, and childbirth. The APR is thought to play a major adaptive and defense role [1]. Because of its immunological and metabolic functions, the liver plays a crucial role in APR. This chapter reviews the early events following the initial trauma, the major soluble mediators, the principal systemic changes, and the liver APR and its regulation." @default.
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- W45542595 date "1995-01-01" @default.
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- W45542595 title "Hepatic Acute-Phase Response" @default.
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- W45542595 doi "https://doi.org/10.1007/978-3-642-79715-6_5" @default.
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