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- W45706097 abstract "textabstractLymphoid cells and macrophages play an important role inthe development and rnaintance of humoral and cellular immunityin mammals. The lymphoid cells in the peripheral lymphoid organsare divided into two major classes: (1) thymus-derivedlymphocytes or T cells and (2) bursa-equivalent-derivedlymphocytes or B cells. Humoral immune responses to mostantigens require interaction between macrophages, T cells andB cells. Antigen-stimulated T cells do not produce antibodiesbut secrete regulatory substances which have a stimulatingor a suppressive effect on the differentiation of antigenstimulatedB cells into antibody-producing plasma cells.The macrophage plays an important role in this T-B interactionby concentrating the antigen by endocytosis and presentinga part of it in a persisting immunogenic form on its cellmembrane. Several aspects of the regulatory influence of theT cell on the humoral (B) immune system were investigatedin our laboratory and the results of our experiments arepresented in the papers added to this thesis." @default.
- W45706097 created "2016-06-24" @default.
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- W45706097 date "1975-12-17" @default.
- W45706097 modified "2023-09-28" @default.
- W45706097 title "T cells and the humoral immune system" @default.
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