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- W45915237 abstract "The lymphomas, as a group, are among the most responsive of neoplastic diseases man falls heir to. The modern period of the chemotherapy of the lymphomas began in the early 1940’s with the appearance of the prototype alkylating agent, nitrogen mustard. While these agents have proven useful in the therapy of these diseases, there is no hard evidence that the life of patients with lymphomas has been significantly prolonged. In the twenty-five years that followed the introduction of nitrogen mustard, oncologists have been concerned primarily with the identification of new active drugs, at first new alkylating agents, but then other classes of antitumor drugs without cross resistance to the alkylating agents. In addition, a great deal of effort has been spent accumulating knowledge about the optimum way of employing each drug. Now that several classes of drugs with independent antilymphoma activity are available, recent studies have been more properly concerned with the best ways to employ them as a group, either used concomitantly, or in sequence in cyclical fashion, to prolong the life of patients, or if possible, to totally eradicate the disease." @default.
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- W45915237 date "1971-01-01" @default.
- W45915237 modified "2023-09-23" @default.
- W45915237 title "Chemotherapy of the Lymphomas" @default.
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- W45915237 doi "https://doi.org/10.1007/978-3-642-46259-7_18" @default.
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