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- W46114600 abstract "To examine possible adverse effects on pituitary function of long-term administration of gonadotropin-releasing hormone agonist (GnRH-a).Prospective analysis of blood sampling before, during, and after GnRH-a therapy.Tertiary institutional outpatient care.Twelve normally ovulatory women with a diagnosis of endometriosis.Six-month suppression with GnRH-a.Serum levels of follicle-stimulating hormone, luteinizing hormone, free thyroxin index, cortisol (F), growth hormone (GH), prolactin (PRL), and thyroid-stimulating hormone (TSH).Basal and stimulated values of gonadotropins, PRL, F, TSH, and GH were normal and unchanged by 6 months of GnRH-a after resumption of menses.Utilizing dynamic pituitary function tests, we were unable to demonstrate an adverse effect of long-term GnRH-a therapy on pituitary function." @default.
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- W46114600 date "1992-12-01" @default.
- W46114600 modified "2023-10-16" @default.
- W46114600 title "Pituitary function before, during, and after chronic gonadotropin-releasing hormone agonist therapy" @default.
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- W46114600 doi "https://doi.org/10.1016/s0015-0282(16)55551-4" @default.
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